» Articles » PMID: 19335964

Diagnostic Splenectomy for Visceral Leishmaniasis

Overview
Specialty General Surgery
Date 2009 Apr 2
PMID 19335964
Citations 1
Authors
Affiliations
Soon will be listed here.
Abstract

A 57-year-old-man with a history of malaise, fever, night sweats and shortness of breath presented a diagnostic challenge to his medical team. He was pancytopaenic and had splenomegaly on admission but other investigations, including bone marrow aspiration, proved inconclusive. After the patient deteriorated clinically, the general surgical team was requested to perform a diagnostic splenectomy. The histology of this showed infection with visceral leishmaniasis. He recovered completely with Amphotericin treatment. Although this is a rare condition, particularly for the general surgeon, this case highlights the difficult position surgeons are often put in when performing major surgery diagnostically.

Citing Articles

Schistosoma mansoni Eggs in Spleen and Lungs, Mimicking Other Diseases.

Gobbi F, Martelli G, Attard L, Buonfrate D, Angheben A, Marchese V PLoS Negl Trop Dis. 2015; 9(7):e0003860.

PMID: 26204263 PMC: 4512674. DOI: 10.1371/journal.pntd.0003860.

References
1.
Malik A, John L, Bruceson A, Lockwood D . Changing pattern of visceral leishmaniasis, United Kingdom, 1985-2004. Emerg Infect Dis. 2006; 12(8):1257-9. PMC: 3291201. DOI: 10.3201/eid1708.050486. View

2.
Sundar S, Chakravarty J, Rai V, Agrawal N, Singh S, Chauhan V . Amphotericin B treatment for Indian visceral leishmaniasis: response to 15 daily versus alternate-day infusions. Clin Infect Dis. 2007; 45(5):556-61. DOI: 10.1086/520665. View

3.
da Silva M, Stewart J, Costa C . Sensitivity of bone marrow aspirates in the diagnosis of visceral leishmaniasis. Am J Trop Med Hyg. 2005; 72(6):811-4. View

4.
Singh S, Sivakumar R . Recent advances in the diagnosis of leishmaniasis. J Postgrad Med. 2003; 49(1):55-60. DOI: 10.4103/0022-3859.927. View

5.
Chappuis F, Rijal S, Soto A, Menten J, Boelaert M . A meta-analysis of the diagnostic performance of the direct agglutination test and rK39 dipstick for visceral leishmaniasis. BMJ. 2006; 333(7571):723. PMC: 1592383. DOI: 10.1136/bmj.38917.503056.7C. View