Prevalence of Allergic Rhinitis in 3-6-year-old Children in Wuhan of China

Background: Only a few prevalence studies of allergic rhinitis (AR) have been reported in China. This study aimed to evaluate the prevalence of AR in a population of 3-6-year-old children in Wuhan, China.

Methods: Sixteen kindergartens in Wuhan City were randomly selected; for each kindergarten, there were three classes from three grades (top, middle and bottom grade, 3-6 years old, respectively). Questionnaires generated by the authors were distributed and filled out by parents of the selected children, with a telephone interview subsequently. Skin prick test (SPT) was carried out on the children after a written consent was signed by the parents.

Results: A total of 1211 (89.5%) valid questionnaires were returned for evaluation. The adjusted current prevalence of AR in 3-6-year-old children was 10.8% with the diagnostic criterion of nasal symptoms(+) and SPTs(+). In the SPTs(+) children, the most common inhalant allergen was house dust mites (94.7%), followed by moulds (28.4%). The prevalence of AR was higher in males than that in females (13.0% vs. 7.7%, P < 0.05). 15.8% and 23.2% of AR children were sensitive to egg and milk, respectively. The percentage of children sensitive to both inhalant and food allergens was 27.4%.

Conclusions: We found an unexpectedly high prevalence of diagnosed AR in 3-6-year-old children within the investigated population. Dust mite was the most important allergen source for 3-6-year-old children in Wuhan.