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Isolation and Comparison of Murine Leukemia Virus-related Glycoproteins from AKR and New Zealand Mice

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Journal J Virol
Date 1977 Apr 1
PMID 192911
Citations 1
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Abstract

The major glycoprotein (gp70) of murine leukemia virus occurs free of virus in the serum and body fluids of certain strains of mice. These glycoproteins were isolated from New Zealand Black mouse (NZB) ascites fluid and from AKR and New Zealand White mouse (NZW) serum by immunoaffinity chromatography and were compared by immunological tests and peptide mapping. Glycoproteins gp70-NZB and gp70-NZW were indistinguishable by all criteria tested and were more closely related to gp70 from Moloney leukemia virus than was gp70-AKR.

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Induction of high serum levels of retroviral env gene products (gp70) in mice by bacterial lipopolysaccharide.

Hara I, Izui S, McCONAHEY P, Elder J, JENSEN F, Dixon F Proc Natl Acad Sci U S A. 1981; 78(7):4397-401.

PMID: 7027259 PMC: 319797. DOI: 10.1073/pnas.78.7.4397.

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