Gastric Myoelectrical Activity in Patients with Primary Biliary Cirrhosis

Overview

Journal J Gastroenterol

Specialty Gastroenterology

Date 2009 Mar 10

PMID 19271110

Authors

Anna Kasicka-Jonderko

Beata Krusiec-Swidergol

Krzysztof Jonderko

Joanna Musialik

Maciej Gonciarz

Barbara Blonska-Fajfrowska

Zbigniew Gonciarz

Affiliations

Soon will be listed here.

Abstract

Objective: To examine gastric myoelectrical activity in patients with primary biliary cirrhosis (PBC).

Materials And Methods: The study comprised 11 female PBC patients (average age 53.4 years, range 43-70) and two aged-matched control groups: 11 (53.4 years, range 37-78) healthy women, and 10 female patients with chronic hepatitis C, CHC (53.9 years, range 35-66), who were examined prior to administration of an antiviral therapy. Every subject underwent an electrogastrographic recording comprising a 30-min interdigestive and a 120-min postprandial period.

Results: Abnormal electrogastrograms, containing prolonged epochs of tachygastria in the postprandial phase were found in 2 out of 11 (18.2%) patients having both stage IV of the Scheuer's PBC classification, as well as in 1 patient out of 10 (10%) with CHC at stage F2 according to the METAVIR fibrosis score.

Conclusion: Electrogastrographic abnormalities do not seem to be pathognomonic for the PBC as a disease, but rather would be considered an unspecific sequel of a morbid liver affection.

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