Body Composition Assessment by Dual-energy X-ray Absorptiometry (DXA)

Overview

Journal Radiol Med

Specialty Radiology

Date 2009 Mar 7

PMID 19266259

Citations 79

Authors

A Andreoli

G Scalzo

S Masala

U Tarantino

G Guglielmi

Affiliations

Soon will be listed here.

Abstract

Body composition (BC) assessment is indispensable to evaluate nutritional status and thus health, both at the population and individual level, and to assess the efficacy of primary and secondary preventive nutritional strategies. Changes in BC, including the regional distribution of body fat, largely occur during pubertal transition, with marked differences between genders. They may, however, also occur in the elderly, who experience significant changes in the ratio between body fat and muscle with aging. The development and implementation of more sophisticated techniques (e.g. BC assessment at the molecular and atomic levels) could provide a major contribution to determining BC at different levels. This review discusses the application of dual-energy X-ray absorptiometry (DXA) on BC determination, given that DXA has the potential to provide overall and regional assessment of BC in terms of fat, lean mass and bone. DXA is widely used in many clinical settings primarily diagnosis osteoporosis. This article describes the use of whole-body DXA in assessing BC in patients with chronic diseases (e.g. metabolic syndrome) as well as in different sport activities to evaluate the effects of exercise.

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References

. Assessment of fracture risk and its application to screening for postmenopausal osteoporosis. Report of a WHO Study Group. World Health Organ Tech Rep Ser. 1994; 843:1-129. View

Chen Z, Wang Z, Lohman T, Heymsfield S, Outwater E, Nicholas J . Dual-energy X-ray absorptiometry is a valid tool for assessing skeletal muscle mass in older women. J Nutr. 2007; 137(12):2775-80. DOI: 10.1093/jn/137.12.2775. View

Shaw K, Srikanth V, Fryer J, Blizzard L, Dwyer T, Venn A . Dual energy X-ray absorptiometry body composition and aging in a population-based older cohort. Int J Obes (Lond). 2006; 31(2):279-84. DOI: 10.1038/sj.ijo.0803417. View

Silvestre R, Kraemer W, West C, Judelson D, Spiering B, Vingren J . Body composition and physical performance during a National Collegiate Athletic Association Division I men's soccer season. J Strength Cond Res. 2006; 20(4):962-70. DOI: 10.1519/R-18165.1. View

Wong S, Janssen I, Ross R . Abdominal adipose tissue distribution and metabolic risk. Sports Med. 2003; 33(10):709-26. DOI: 10.2165/00007256-200333100-00001. View

Bell W, Evans W, Cobner D, Eston R . Regional placement of bone mineral mass, fat mass, and lean soft tissue mass in young adult rugby union players. Ergonomics. 2005; 48(11-14):1462-72. DOI: 10.1080/00140130500101007. View

De Lorenzo A, Bertini I, Candeloro N, Iacopino L, Andreoli A, Van Loan M . Comparison of different techniques to measure body composition in moderately active adolescents. Br J Sports Med. 1998; 32(3):215-9. PMC: 1756100. DOI: 10.1136/bjsm.32.3.215. View

Lands L, Hornby L, Hohenkerk J, Glorieux F . Accuracy of measurements of small changes in soft-tissue mass by dual-energy x-ray absorptiometry. Clin Invest Med. 1996; 19(4):279-85. View

Volgyi E, Tylavsky F, Lyytikainen A, Suominen H, Alen M, Cheng S . Assessing body composition with DXA and bioimpedance: effects of obesity, physical activity, and age. Obesity (Silver Spring). 2008; 16(3):700-5. DOI: 10.1038/oby.2007.94. View

10.

Peppler W, Mazess R . Total body bone mineral and lean body mass by dual-photon absorptiometry. I. Theory and measurement procedure. Calcif Tissue Int. 1981; 33(4):353-9. DOI: 10.1007/BF02409455. View

11.

Blake G, Fogelman I . Dual energy x-ray absorptiometry and its clinical applications. Semin Musculoskelet Radiol. 2003; 6(3):207-18. DOI: 10.1055/s-2002-36718. View

12.

Deedwania P, Volkova N . Current Treatment Options for the Metabolic Syndrome. Curr Treat Options Cardiovasc Med. 2005; 7(1):61-74. DOI: 10.1007/s11936-005-0007-1. View

13.

Tylavsky F, Lohman T, Dockrell M, Lang T, Schoeller D, Wan J . Comparison of the effectiveness of 2 dual-energy X-ray absorptiometers with that of total body water and computed tomography in assessing changes in body composition during weight change. Am J Clin Nutr. 2003; 77(2):356-63. DOI: 10.1093/ajcn/77.2.356. View

14.

Heer M, Kamps N, Biener C, Korr C, BOERGER A, Zittermann A . Calcium metabolism in microgravity. Eur J Med Res. 1999; 4(9):357-60. View

15.

Kelly T, Berger N, Richardson T . DXA body composition: theory and practice. Appl Radiat Isot. 1998; 49(5-6):511-3. DOI: 10.1016/s0969-8043(97)00226-1. View

16.

Roubenoff R, Hughes V . Sarcopenia: current concepts. J Gerontol A Biol Sci Med Sci. 2000; 55(12):M716-24. DOI: 10.1093/gerona/55.12.m716. View

17.

Genton L, Hans D, Kyle U, Pichard C . Dual-energy X-ray absorptiometry and body composition: differences between devices and comparison with reference methods. Nutrition. 2002; 18(1):66-70. DOI: 10.1016/s0899-9007(01)00700-6. View

18.

Park Y, Heymsfield S, Gallagher D . Are dual-energy X-ray absorptiometry regional estimates associated with visceral adipose tissue mass?. Int J Obes Relat Metab Disord. 2002; 26(7):978-83. DOI: 10.1038/sj.ijo.0801982. View

19.

de Jong N, Chin A Paw M, de Groot L, Hiddink G, van Staveren W . Dietary supplements and physical exercise affecting bone and body composition in frail elderly persons. Am J Public Health. 2000; 90(6):947-54. PMC: 1446257. DOI: 10.2105/ajph.90.6.947. View

20.

Pietrobelli A, Wang Z, Formica C, Heymsfield S . Dual-energy X-ray absorptiometry: fat estimation errors due to variation in soft tissue hydration. Am J Physiol. 1998; 274(5):E808-16. DOI: 10.1152/ajpendo.1998.274.5.E808. View