New 17-methyl-13-octadecenoic and 3,16-docosadienoic Acids from the Sponge Polymastia Penicillus

Overview

Journal Lipids

Specialty Biochemistry

Date 2009 Mar 7

PMID 19266225

Citations 6

Authors

Claire Denis

Gaetane Wielgosz-Collin

Anne Breteche

Nicolas Ruiz

Vony Rabesaotra

Nicole Boury-Esnault

Jean-Michel Kornprobst

Gilles Barnathan

Affiliations

Soon will be listed here.

Abstract

The phospholipid fatty acid composition of the North-East Atlantic sponge Polymastia penicillus (South Brittany, France) was investigated. Sixty fatty acids (FA) were identified as methyl esters (FAME) and N-acyl pyrrolidides (NAP) by gas chromatography-mass spectrometry (GC/MS), including eight Delta5,9 unsaturated FA and three long-chain 2-hydroxylated FA. The major phospholipid FA were palmitic (14.3% of the total FA mixture), vaccenic (12.7%), 15(Z)-docosenoic (13.4%) and 5(Z),9(Z)-hexacosadienoic (13.3%) acids. In addition to the iso- and anteiso-branched saturated FA, several unusual short-chain branched saturated FA were identified. In addition to the known Delta5,9 FA, and interestingly regarding their identification by GC-MS as N-acyl pyrrolidides, was the co-occurrence of unusual FA possessing a Delta3, Delta4 and Delta5 double bond such as iso-4-pentadecenoic, iso-5-heptadecenoic, anteiso-5-heptadecenoic and two new compounds, not hitherto found in nature, namely 17-methyl-13-octadecenoic (0.8%) and 3,16-docosadienoic (1.1%) acids.

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