Ratiometric Single-nanoparticle Oxygen Sensors for Biological Imaging

Overview

Journal Angew Chem Int Ed Engl

Specialty Chemistry

Date 2009 Mar 3

PMID 19253320

Citations 60

Authors

Changfeng Wu

Barbara Bull

Kenneth Christensen

Jason McNeill

Affiliations

Soon will be listed here.

Abstract

It makes sense: Conjugated polymer nanoparticles doped with a platinum porphyrin dye exhibit bright phosphorescence that is highly sensitive to the concentration of molecular oxygen. The small size, extraordinary brightness, excellent sensitivity, and ratiometric emission, together with the demonstration of single-particle sensing and cellular uptake, indicate the potential of the nanoparticle sensors for quantitative mapping of local molecular oxygen concentration.

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