Diabetes in African American Youth: Prevalence, Incidence, and Clinical Characteristics: the SEARCH for Diabetes in Youth Study

Overview

Journal Diabetes Care

Specialty Endocrinology

Date 2009 Feb 28

PMID 19246576

Citations 80

Authors

Elizabeth J Mayer-Davis

Jennifer Beyer

Ronny A Bell

Dana Dabelea

Ralph DAgostino Jr

Giuseppina Imperatore

Jean M Lawrence

Angela D Liese

Lenna Liu

Santica Marcovina

Beatriz Rodriguez

Affiliations

Soon will be listed here.

Abstract

Objective: To report the prevalence and incidence of type 1 and type 2 diabetes among African American youth and to describe demographic, clinical, and behavioral characteristics.

Research Design And Methods: Data from the SEARCH for Diabetes in Youth Study, a population-based, multicenter observational study of youth with clinically diagnosed diabetes aged 0-19 years, were used to estimate the prevalence for calendar year 2001 (692 cases) and incidence based on 748 African American case subjects diagnosed in 2002-2005. Characteristics of these youth were obtained during a research visit for 436 African American youth with type 1 diabetes and 212 African American youth with type 2 diabetes.

Results: Among African American youth aged 0-9 years, prevalence (per 1,000) of type 1 diabetes was 0.57 (95% CI 0.47-0.69) and for those aged 10-19 years 2.04 (1.85-2.26). Among African American youth aged 0-9 years, annual type 1 diabetes incidence (per 100,000) was 15.7 (13.7-17.9) and for those aged 10-19 years 15.7 (13.8-17.8). A1C was >or=9.5% among 50% of youth with type 1 diabetes aged >or=15 years. Across age-groups and sex, 44.7% of African American youth with type 1 diabetes were overweight or obese. Among African American youth aged 10-19 years, prevalence (per 1,000) of type 2 diabetes was 1.06 (0.93-1.22) and annual incidence (per 100,000) was 19.0 (16.9-21.3). About 60% of African American youth with type 2 diabetes had an annual household income of <$25,000. Among those aged >or=15 years, 27.5% had an A1C >or=9.5%, 22.5% had high blood pressure, and, across subgroups of age and sex, >90% were overweight or obese.

Conclusions: Type 1 diabetes presents a serious burden among African American youth aged <10 years, and African American adolescents are impacted substantially by both type 1 and type 2 diabetes.

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References

Smith T, Drum M, Lipton R . Incidence of childhood type I and non-type 1 diabetes mellitus in a diverse population: the Chicago Childhood Diabetes Registry, 1994 to 2003. J Pediatr Endocrinol Metab. 2007; 20(10):1093-107. DOI: 10.1515/jpem.2007.20.10.1093. View

Lawrence J, Standiford D, Loots B, Klingensmith G, Williams D, Ruggiero A . Prevalence and correlates of depressed mood among youth with diabetes: the SEARCH for Diabetes in Youth study. Pediatrics. 2006; 117(4):1348-58. DOI: 10.1542/peds.2005-1398. View

Ford E, Giles W, Dietz W . Prevalence of the metabolic syndrome among US adults: findings from the third National Health and Nutrition Examination Survey. JAMA. 2002; 287(3):356-9. DOI: 10.1001/jama.287.3.356. View

Li S, Chen W, Srinivasan S, Tang R, Bond M, Berenson G . Race (black-white) and gender divergences in the relationship of childhood cardiovascular risk factors to carotid artery intima-media thickness in adulthood: the Bogalusa Heart Study. Atherosclerosis. 2006; 194(2):421-5. DOI: 10.1016/j.atherosclerosis.2006.08.026. View

Dabelea D, DAgostino Jr R, Mayer-Davis E, Pettitt D, Imperatore G, Dolan L . Testing the accelerator hypothesis: body size, beta-cell function, and age at onset of type 1 (autoimmune) diabetes. Diabetes Care. 2006; 29(2):290-4. DOI: 10.2337/diacare.29.02.06.dc05-1339. View

Rodriguez B, Fujimoto W, Mayer-Davis E, Imperatore G, Williams D, Bell R . Prevalence of cardiovascular disease risk factors in U.S. children and adolescents with diabetes: the SEARCH for diabetes in youth study. Diabetes Care. 2006; 29(8):1891-6. DOI: 10.2337/dc06-0310. View

Auslander W, Thompson S, Dreitzer D, White N, Santiago J . Disparity in glycemic control and adherence between African-American and Caucasian youths with diabetes. Family and community contexts. Diabetes Care. 1997; 20(10):1569-75. DOI: 10.2337/diacare.20.10.1569. View

Banerji M . Diabetes in African Americans: unique pathophysiologic features. Curr Diab Rep. 2004; 4(3):219-23. DOI: 10.1007/s11892-004-0027-3. View

Ingram D, Parker J, Schenker N, Weed J, Hamilton B, Arias E . United States Census 2000 population with bridged race categories. Vital Health Stat 2. 2003; (135):1-55. View

10.

Dabelea D, Bell R, DAgostino Jr R, Imperatore G, Johansen J, Linder B . Incidence of diabetes in youth in the United States. JAMA. 2007; 297(24):2716-24. DOI: 10.1001/jama.297.24.2716. View

11.

Adams A, Trinacty C, Zhang F, Kleinman K, Grant R, Meigs J . Medication adherence and racial differences in A1C control. Diabetes Care. 2008; 31(5):916-21. PMC: 2563955. DOI: 10.2337/dc07-1924. View

12.

Kershnar A, Daniels S, Imperatore G, Palla S, Petitti D, Pettitt D . Lipid abnormalities are prevalent in youth with type 1 and type 2 diabetes: the SEARCH for Diabetes in Youth Study. J Pediatr. 2006; 149(3):314-9. DOI: 10.1016/j.jpeds.2006.04.065. View

13.

Molitch M, DeFronzo R, Franz M, Keane W, Mogensen C, Parving H . Nephropathy in diabetes. Diabetes Care. 2003; 27 Suppl 1:S79-83. DOI: 10.2337/diacare.27.2007.s79. View

14.

Misra A, Ganda O . Migration and its impact on adiposity and type 2 diabetes. Nutrition. 2007; 23(9):696-708. DOI: 10.1016/j.nut.2007.06.008. View

15.

Rewers A, Klingensmith G, Davis C, Petitti D, Pihoker C, Rodriguez B . Presence of diabetic ketoacidosis at diagnosis of diabetes mellitus in youth: the Search for Diabetes in Youth Study. Pediatrics. 2008; 121(5):e1258-66. DOI: 10.1542/peds.2007-1105. View

16.

Muntner P, He J, Cutler J, Wildman R, Whelton P . Trends in blood pressure among children and adolescents. JAMA. 2004; 291(17):2107-13. DOI: 10.1001/jama.291.17.2107. View

17.

Mokdad A, Ford E, Bowman B, Dietz W, Vinicor F, Bales V . Prevalence of obesity, diabetes, and obesity-related health risk factors, 2001. JAMA. 2002; 289(1):76-9. DOI: 10.1001/jama.289.1.76. View

18.

Wang M, Kim S, Gonzalez A, MacLeod K, Winkleby M . Socioeconomic and food-related physical characteristics of the neighbourhood environment are associated with body mass index. J Epidemiol Community Health. 2007; 61(6):491-8. PMC: 2465719. DOI: 10.1136/jech.2006.051680. View

19.

Crook E, Patel S . Diabetic nephropathy in African-American patients. Curr Diab Rep. 2004; 4(6):455-61. DOI: 10.1007/s11892-004-0056-y. View

20.

Delamater A, Shaw K, Applegate E, Pratt I, Eidson M, Lancelotta G . Risk for metabolic control problems in minority youth with diabetes. Diabetes Care. 1999; 22(5):700-5. DOI: 10.2337/diacare.22.5.700. View