Social Environmental Stressors, Psychological Factors, and Kidney Disease

Overview

Journal J Investig Med

Publisher Sage Publications

Specialty General Medicine

Date 2009 Feb 26

PMID 19240646

Citations 62

Authors

Marino A Bruce

Bettina M Beech

Mario Sims

Tony N Brown

Sharon B Wyatt

Herman A Taylor

David R Williams

Errol Crook

Affiliations

Soon will be listed here.

Abstract

Kidney disease is one of the most striking examples of health disparities in American public health. Disparities in the prevalence and progression of kidney disease are generally thought to be a function of group differences in the prevalence of kidney disease risk factors such as diabetes, hypertension, and obesity. However, the presence of these comorbidities does not completely explain the elevated rate of progression from chronic kidney disease (CKD) to end-stage renal disease among high-risk populations such as African Americans. We believe that the social environment is an important element in the pathway from CKD risk factors to CKD and end-stage renal disease. This review of the literature draws heavily from social science and social epidemiology to present a conceptual frame specifying how social, economic, and psychosocial factors interact to affect the risks for and the progression of kidney disease.

Citing Articles

Financial Toxicity and Kidney Disease in Children and Adults: A Scoping Review.

Siligato R, Gembillo G, De Giorgi A, Di Maria A, Scichilone L, Capone M Int J Nephrol Renovasc Dis. 2025; 18:13-25.

PMID: 39872022 PMC: 11770919. DOI: 10.2147/IJNRD.S485111.

Study of Caregiver Burden in Continuous Ambulatory Peritoneal Dialysis.

Dhareshwar S, Nithin R, Anantharam J, Kedlaya P, Satish R, Jha V Indian J Nephrol. 2024; 34(6):597-602.

PMID: 39649306 PMC: 11618974. DOI: 10.25259/ijn_424_23.

Loneliness, social isolation and incident chronic kidney disease among patients with diabetes.

Tang R, Zhou J, Wang X, Ma H, Li X, Heianza Y Gen Psychiatr. 2024; 37(3):e101298.

PMID: 38859925 PMC: 11163592. DOI: 10.1136/gpsych-2023-101298.

Financial Toxicity in Renal Patients (FINTORE) Study: A Cross-Sectional Italian Study on Financial Burden in Kidney Disease-A Project Protocol.

Siligato R, Gembillo G, Di Simone E, Di Maria A, Nicoletti S, Scichilone L Methods Protoc. 2024; 7(2).

PMID: 38668141 PMC: 11053909. DOI: 10.3390/mps7020034.

Mental health and social-emotional functioning in children and adolescents with chronic kidney disease.

Kogon A, Hooper S Pediatr Nephrol. 2023; 39(7):2015-2031.

PMID: 37878136 DOI: 10.1007/s00467-023-06151-1.

References

Kimmel P, Emont S, Newmann J, Danko H, Moss A . ESRD patient quality of life: symptoms, spiritual beliefs, psychosocial factors, and ethnicity. Am J Kidney Dis. 2003; 42(4):713-21. DOI: 10.1016/s0272-6386(03)00907-7. View

Calhoun D, Mutinga M . Race, family history of hypertension, and sympathetic response to cold pressor testing. Blood Press. 1997; 6(4):209-13. DOI: 10.3109/08037059709062071. View

Uchino B, Cacioppo J, Kiecolt-Glaser J . The relationship between social support and physiological processes: a review with emphasis on underlying mechanisms and implications for health. Psychol Bull. 1996; 119(3):488-531. DOI: 10.1037/0033-2909.119.3.488. View

Kimmel P, Peterson R, Weihs K, Simmens S, Alleyne S, Cruz I . Psychosocial factors, behavioral compliance and survival in urban hemodialysis patients. Kidney Int. 1998; 54(1):245-54. DOI: 10.1046/j.1523-1755.1998.00989.x. View

Coresh J, Selvin E, Stevens L, Manzi J, Kusek J, Eggers P . Prevalence of chronic kidney disease in the United States. JAMA. 2007; 298(17):2038-47. DOI: 10.1001/jama.298.17.2038. View

Robert S . Community-level socioeconomic status effects on adult health. J Health Soc Behav. 1998; 39(1):18-37. View

Shoham D, Vupputuri S, Diez Roux A, Kaufman J, Coresh J, Kshirsagar A . Kidney disease in life-course socioeconomic context: the Atherosclerosis Risk in Communities (ARIC) Study. Am J Kidney Dis. 2007; 49(2):217-26. DOI: 10.1053/j.ajkd.2006.11.031. View

Hedayati S, Bosworth H, Briley L, Sloane R, Pieper C, Kimmel P . Death or hospitalization of patients on chronic hemodialysis is associated with a physician-based diagnosis of depression. Kidney Int. 2008; 74(7):930-6. DOI: 10.1038/ki.2008.311. View

Volkova N, McClellan W, Klein M, Flanders D, Kleinbaum D, Soucie J . Neighborhood poverty and racial differences in ESRD incidence. J Am Soc Nephrol. 2007; 19(2):356-64. PMC: 2396744. DOI: 10.1681/ASN.2006080934. View

10.

Hicks P, Staten J, Palmer N, Langefeld C, Ziegler J, Keene K . Association analysis of the ephrin-B2 gene in African-Americans with end-stage renal disease. Am J Nephrol. 2008; 28(6):914-20. PMC: 2786015. DOI: 10.1159/000141934. View

11.

HARRIS C, Edwards J, Baruch A, RILEY W, Pusser B, Rejeski W . Effects of mental stress on brachial artery flow-mediated vasodilation in healthy normal individuals. Am Heart J. 2000; 139(3):405-11. DOI: 10.1016/s0002-8703(00)90083-8. View

12.

Krieger N, Sidney S . Racial discrimination and blood pressure: the CARDIA Study of young black and white adults. Am J Public Health. 1996; 86(10):1370-8. PMC: 1380646. DOI: 10.2105/ajph.86.10.1370. View

13.

House J, Landis K, Umberson D . Social relationships and health. Science. 1988; 241(4865):540-5. DOI: 10.1126/science.3399889. View

14.

Miller T, Smith T, Turner C, Guijarro M, Hallet A . A meta-analytic review of research on hostility and physical health. Psychol Bull. 1996; 119(2):322-48. DOI: 10.1037/0033-2909.119.2.322. View

15.

Xu J, Li G, Wang P, Velazquez H, Yao X, Li Y . Renalase is a novel, soluble monoamine oxidase that regulates cardiac function and blood pressure. J Clin Invest. 2005; 115(5):1275-80. PMC: 1074681. DOI: 10.1172/JCI24066. View

16.

Krieger N . Theories for social epidemiology in the 21st century: an ecosocial perspective. Int J Epidemiol. 2001; 30(4):668-77. DOI: 10.1093/ije/30.4.668. View

17.

Norris K, Mehrotra R, Nissenson A . Racial differences in mortality and ESRD. Am J Kidney Dis. 2008; 52(2):205-8. PMC: 2601720. DOI: 10.1053/j.ajkd.2008.06.004. View

18.

House J . Social isolation kills, but how and why?. Psychosom Med. 2001; 63(2):273-4. DOI: 10.1097/00006842-200103000-00011. View

19.

Diez Roux A, Merkin S, Arnett D, Chambless L, Massing M, Nieto F . Neighborhood of residence and incidence of coronary heart disease. N Engl J Med. 2001; 345(2):99-106. DOI: 10.1056/NEJM200107123450205. View

20.

Cukor D, Peterson R, Cohen S, Kimmel P . Depression in end-stage renal disease hemodialysis patients. Nat Clin Pract Nephrol. 2006; 2(12):678-87. DOI: 10.1038/ncpneph0359. View