Effect of Mouthrinse Containing Propolis on Oral Microorganisms and Human Gingival Fibroblasts

Overview

Journal Eur J Dent

Publisher Thieme

Specialty Dentistry

Date 2009 Feb 13

PMID 19212467

Citations 48

Authors

Fatih Ozan

Zeynep Sumer

Zubeyde Akin Polat

Kursat Er

Ulku Ozan

Orhan Deger

Affiliations

Soon will be listed here.

Abstract

Objectives: The aim of this study was to compare the effects of four different mouthrinse containing propolis solutions and mouthrinse containing 0.2% chlorhexidine (CHX) on oral microorganisms and human gingival fibroblasts.

Methods: Four different solutions of propolis were prepared and propylene glycol and alcohol were used as solvents for each propolis sample. Mouthrinse containing propolis was prepared at four different concentrations as 10%, 5%, 2.5% and 1%. Besides, CHX was used as control group. The antibacterial effects of five solutions on oral microorganisms were tested and their cytotoxic effects on human gingival fibroblasts were evaluated by agar diffusion test.

Results: At this concentrations effectiveness of mouthrinse containing propolis samples on oral microorganisms were not found as effective as CHX. On the contrary, samples found less cytotoxic on human gingival fibroblasts than CHX.

Conclusions: Standardized preparations of propolis can be used as a mouthrinse at appropriate concentrations. To obtain a standardized chemical composition, advanced researches are needed.

Citing Articles

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Comparison of cytotoxic and apoptosis-inducing effects of MTA, propolis, and propolis-MTA on immature dental pulp stem cells.

Nazemi Salman B, Kalantari M, Mohebbi Rad M, Saburi E Eur Arch Paediatr Dent. 2023; 24(6):797-802.

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Arab S, Bahador A, Sodagar A, Pourhajibagher M, Akhavan A, Hafith A Front Dent. 2022; 18:29.

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