Pharmacological Management of Acute Bronchiolitis

Overview

Journal Ther Clin Risk Manag

Publisher Dove Medical Press

Date 2009 Feb 12

PMID 19209271

Citations 5

Authors

Melvin Wright

Charles J Mullett

Giovanni Piedimonte

Affiliations

Soon will be listed here.

Abstract

This article reviews the current knowledge base related to the pharmacological treatments for acute bronchiolitis. Bronchiolitis is a common lower respiratory illness affecting infants worldwide. The mainstays of therapy include airway support, supplemental oxygen, and support of fluids and nutrition. Frequently tried pharmacological interventions, such as ribavirin, nebulized bronchodilators, and systemic corticosteroids, have not been proven to benefit patients with bronchiolitis. Antibiotics do not improve the clinical course of patients with bronchiolitis, and should be used only in those patients with proven concurrent bacterial infection. Exogenous surfactant and heliox therapy also cannot be recommended for routine use, but surfactant replacement holds promise and should be further studied.

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