Work Loss and Work Entry Among Persons with Systemic Lupus Erythematosus: Comparisons with a National Matched Sample

Overview

Journal Arthritis Rheum

Specialty Rheumatology

Date 2009 Jan 30

PMID 19177546

Citations 17

Authors

Edward Yelin

Chris Tonner

Laura Trupin

Pantelis Panopalis

Jinoos Yazdany

Laura Julian

Patricia Katz

Lindsey A Criswell

Affiliations

Soon will be listed here.

Abstract

Objective: To prospectively track work loss among those employed and work entry among those not employed in a cohort of persons with systemic lupus erythematosus (SLE), assess risk factors for these outcomes, and compare rates of the outcomes with a matched national sample.

Methods: The present study analyzed 4 years of data from the Lupus Outcomes Study (LOS), augmented by information on the local labor market from the Census Bureau and the Bureau of Labor Statistics. We used the Kaplan-Meier method to assess time from study initiation until work loss or work entry, and Cox proportional hazards regression to estimate factors affecting these outcomes. Finally, we compared rates of work loss and work entry in the LOS with rates in the Survey of Income and Program Participation (SIPP).

Results: At study initiation, 394 LOS participants (51%) were employed, of whom 92 (23.4%) experienced work loss. In multivariate analysis, older age, lower cognitive and physical functioning, and higher reports of depressive symptoms predicted work loss. In comparison with the SIPP sample, rates of work loss did not differ. Of the 376 LOS participants not employed, 76 (20.2%) experienced work entry. In multivariate analysis, less disease activity, fewer lung manifestations, better physical functioning, and shorter time since last employment predicted work entry. In comparison with the SIPP, rates of work entry were only lower between ages 35 and 55 years.

Conclusion: Until age 55 years, low rates of employment among persons with SLE may be due to lower rates of work entry rather than higher rates of work loss. Beyond age 55 years, both high rates of work loss and low rates of work entry contribute to low rates of employment.

Citing Articles

Development of the American College of Rheumatology Patient-Reported Outcome Quality Measures for Systemic Lupus Erythematosus.

Katz P, Barber C, Duarte-Garcia A, Garg S, Machua W, Rodgers W Arthritis Care Res (Hoboken). 2024; 76(6):777-787.

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Work participation in patients with systematic lupus erythematosus: a systematic review.

Blomjous B, Gajadin G, Voskuyl A, Falzon L, Hoving J, Bultink I Rheumatology (Oxford). 2021; 61(7):2740-2754.

PMID: 34792543 PMC: 9258549. DOI: 10.1093/rheumatology/keab855.

Employment exit and entry among U.S. adults with and without arthritis during the Great Recession. A longitudinal study: 2007-2009, NHIS/MEPS.

Theis K, Roblin D, Helmick C, Luo R Work. 2018; 60(2):303-318.

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Productivity Losses and Costs in the Less-Common Systemic Autoimmune Rheumatic Diseases.

McCormick N, Marra C, Avina-Zubieta J Curr Rheumatol Rep. 2017; 19(11):72.

PMID: 29086172 DOI: 10.1007/s11926-017-0698-9.

Efficacy of a Work Disability Prevention Program for People with Rheumatic and Musculoskeletal Conditions: A Single-Blind Parallel-Arm Randomized Controlled Trial.

Keysor J, LaValley M, Brown C, Felson D, Alheresh R, Vaughan M Arthritis Care Res (Hoboken). 2017; 70(7):1022-1029.

PMID: 28941189 PMC: 6374024. DOI: 10.1002/acr.23423.

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