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PNIPAM Gel-coated Gold Nanorods for Targeted Delivery Responding to a Near-infrared Laser

Overview
Journal Bioconjug Chem
Specialty Biochemistry
Date 2009 Jan 13
PMID 19133725
Citations 29
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Abstract

Gold nanorods can be used as photothermal converters, permitting near-infrared (NIR) light to be transmitted deep into tissues without causing damage. We prepared hybrid nanorods with a core-shell structure, i.e., a single gold nanorod encapsulated in a poly (N-isopropylacrylamide) nanogel. Hybrid nanorods demonstrated remote, reversible, pulsatile phase transition and in vivo action after irradiation using a NIR laser.

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