Computed Tomography of the Gastrointestinal Manifestation of Hereditary Angioedema

Overview

Journal Radiat Med

Specialties Nuclear Medicine
Oncology
Radiology

Date 2009 Jan 10

PMID 19132494

Citations 5

Authors

Masaki Wakisaka

Mitsutaka Shuto

Hisanori Abe

Masaaki Tajima

Hidefumi Shiroshita

Toshio Bandoh

Tsuyoshi Arita

Michio Kobayashi

Tomoko Nakayama

Fumito Okada

Hiromu Mori

Naoki Uemura

Affiliations

Soon will be listed here.

Abstract

We report a case of gastrointestinal manifestation of hereditary angioedema. Computed tomography (CT) revealed wall thickening of the gastric antrum, duodenum, and jejunum. Dilatation of the third part of the duodenum, thickening of the small bowel mesentery and omentum, and retroperitoneal edema were present. The importance of considering this condition in patients presenting such CT findings correlated with the appropriate history is discussed.

Citing Articles

Abdominal and pelvic imaging in the diagnosis of acute abdominal attacks in patients with hereditary angioedema due to C1-inhibitor deficiency.

Obtulowicz P, Stobiecki M, Dyga W, Juchacz A, Popiela T, Obtulowicz K Postepy Dermatol Alergol. 2022; 39(4):749-756.

PMID: 36090726 PMC: 9454366. DOI: 10.5114/ada.2021.108438.

Hereditary Angioedema and Gastrointestinal Complications: An Extensive Review of the Literature.

Patel N, Suarez L, Kapur S, Bielory L Case Reports Immunol. 2015; 2015:925861.

PMID: 26339513 PMC: 4538593. DOI: 10.1155/2015/925861.

Hereditary angioedema: imaging manifestations and clinical management.

Gakhal M, Marcotte G Emerg Radiol. 2014; 22(1):83-90.

PMID: 24880254 DOI: 10.1007/s10140-014-1242-0.

[Diagnostics and exclusion of hereditary angioedema : a standarized approach for the practice].

Magerl M, Brasch J, Forster U, Hauswald B, Mohr E, Mohr B Hautarzt. 2012; 63(7):567-72.

PMID: 22751857 DOI: 10.1007/s00105-012-2388-x.

Intestinal angioedema misdiagnosed as recurrent episodes of gastroenteritis.

Locascio E, Mahler S, Arnold T West J Emerg Med. 2010; 11(4):391-4.

PMID: 21079716 PMC: 2967696.

References

Lim Y, Kim J, Shim D, Lim C, Jang H, Shin H . Hereditary angioneurotic edema of the larynx. Acta Otolaryngol. 2005; 125(11):1240-3. DOI: 10.1080/00016480510038185. View

Ciaccia D, Brazer S, Baker M . Acquired C1 esterase inhibitor deficiency causing intestinal angioedema: CT appearance. AJR Am J Roentgenol. 1993; 161(6):1215-6. DOI: 10.2214/ajr.161.6.8249728. View

Talavera A, Larraona J, Ramos J, Lopez T, Maraver A, Arias J . Hereditary angioedema: an infrequent cause of abdominal pain with ascites. Am J Gastroenterol. 1995; 90(3):471-4. View

Fisher A, Fleishman M, Hancock D . Angioedema of the small bowel: CT appearance. AJR Am J Roentgenol. 2000; 175(2):554. DOI: 10.2214/ajr.175.2.1750554. View

DONALDSON V, Evans R . A BIOCHEMICAL ABNORMALITY IN HEREDIATRY ANGIONEUROTIC EDEMA: ABSENCE OF SERUM INHIBITOR OF C' 1-ESTERASE. Am J Med. 1963; 35:37-44. DOI: 10.1016/0002-9343(63)90162-1. View

Kim S, Cho J, Lim H . CT findings of isolated small bowel angioedema due to iodinated radiographic contrast medium reaction. Abdom Imaging. 1999; 24(2):117-9. DOI: 10.1007/s002619900457. View

Sadeghi N, Van Daele D, Hainaux B, Engelholm L, Michel O . Hereditary angio-edema involving the gastrointestinal tract: CT findings. Eur Radiol. 2001; 11(1):99-101. DOI: 10.1007/s003300000568. View

Wei S, Fitzgerald K, Maglinte D . CT findings in small bowel angioedema: a cause of acute abdominal pain. Emerg Radiol. 2007; 13(5):281-3. DOI: 10.1007/s10140-006-0562-0. View

Sekijima Y, Hashimoto T, Koshihara H, Kawachi Y, Otsuka F, Ikeda S . Massive mesenteric edema in a patient with type I hereditary angioedema. Mod Rheumatol. 2006; 15(5):361-3. DOI: 10.1007/s10165-005-0416-8. View

10.

Hermans C . Successful management with C1-inhibitor concentrate of hereditary angioedema attacks during two successive pregnancies: a case report. Arch Gynecol Obstet. 2007; 276(3):271-6. DOI: 10.1007/s00404-007-0329-1. View

11.

Alsenz J, Bork K, Loos M . Autoantibody-mediated acquired deficiency of C1 inhibitor. N Engl J Med. 1987; 316(22):1360-6. DOI: 10.1056/NEJM198705283162202. View

12.

Visentin D, Yang W, Karsh J . C1-esterase inhibitor transfusions in patients with hereditary angioedema. Ann Allergy Asthma Immunol. 1998; 80(6):457-61. DOI: 10.1016/S1081-1206(10)63067-0. View

13.

Shahzad G, Korsten M, Blatt C, Motwani P . Angiotensin-converting enzyme (ACE) inhibitor-associated angioedema of the stomach and small intestine: a case report. Mt Sinai J Med. 2007; 73(8):1123-5. View

14.

Frank M . Complement in the pathophysiology of human disease. N Engl J Med. 1987; 316(24):1525-30. DOI: 10.1056/NEJM198706113162407. View

15.

Nasnas R, Awky J, Aoun N, Haddad S, Slaba S, Atallah N . [Digestive manifestations of hereditary angioneurotic edema. Apropos of a case]. J Radiol. 1998; 78(11):1167-9. View

16.

AGOSTONI A, Cicardi M . Hereditary and acquired C1-inhibitor deficiency: biological and clinical characteristics in 235 patients. Medicine (Baltimore). 1992; 71(4):206-15. DOI: 10.1097/00005792-199207000-00003. View

17.

De Backer A, De Schepper A, Vandevenne J, Schoeters P, Michielsen P, Stevens W . CT of angioedema of the small bowel. AJR Am J Roentgenol. 2001; 176(3):649-52. DOI: 10.2214/ajr.176.3.1760649. View