Oxidase-like Activity of Polymer-coated Cerium Oxide Nanoparticles

Overview

Journal Angew Chem Int Ed Engl

Specialty Chemistry

Date 2009 Jan 9

PMID 19130532

Citations 179

Authors

Atul Asati

Santimukul Santra

Charalambos Kaittanis

Sudip Nath

J Manuel Perez

Affiliations

Soon will be listed here.

Abstract

Inorganic enzyme? Ceria nanoparticles exhibit unique oxidase-like activity at acidic pH values. These redox catalysts can be used in immunoassays (ELISA) when modified with targeting ligands (see picture; light blue and yellow structures are nanoparticles with attached ligands). This modification allows both for binding and for detection by the catalytic oxidation of sensitive colorimetric dyes (e.g. TMB).

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