Cardiovascular, Inflammatory, and Metabolic Consequences of Sleep Deprivation

Overview

Journal Prog Cardiovasc Dis

Specialty Cardiology & Vascular Diseases

Date 2008 Dec 27

PMID 19110131

Citations 322

Authors

Janet M Mullington

Monika Haack

Maria Toth

Jorge M Serrador

Hans K Meier-Ewert

Affiliations

Soon will be listed here.

Abstract

That insufficient sleep is associated with poor attention and performance deficits is becoming widely recognized. Fewer people are aware that chronic sleep complaints in epidemiologic studies have also been associated with an increase in overall mortality and morbidity. This article summarizes findings of known effects of insufficient sleep on cardiovascular risk factors including blood pressure, glucose metabolism, hormonal regulation, and inflammation with particular emphasis on experimental sleep loss, using models of total and partial sleep deprivation, in healthy individuals who normally sleep in the range of 7 to 8 hours and have no sleep disorders. These studies show that insufficient sleep alters established cardiovascular risk factors in a direction that is known to increase the risk of cardiac morbidity.

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