Correct Charge State Assignment of Native Electrospray Spectra of Protein Complexes

Overview

Journal J Am Soc Mass Spectrom

Specialty Chemistry

Date 2008 Dec 24

PMID 19103497

Citations 7

Authors

Lars Liepold

Luke M Oltrogge

Peter A Suci

Mark J Young

Trevor Douglas

Affiliations

Soon will be listed here.

Abstract

Correct charge state assignment is crucial to assigning an accurate mass to supramolecular complexes analyzed by electrospray mass spectrometry. Conventional charge state assignment techniques fall short of reliably and unambiguously predicting the correct charge state for many supramolecular complexes. We provide an explanation of the shortcomings of the conventional techniques and have developed a robust charge state assignment method that is applicable to all spectra.

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