New Genetic Abnormalities and Treatment Response in Acute Lymphoblastic Leukemia

Overview

Journal Semin Hematol

Specialty Hematology

Date 2008 Dec 23

PMID 19100364

Citations 13

Authors

Jules P P Meijerink

Monique L den Boer

Rob Pieters

Affiliations

Soon will be listed here.

Abstract

Numerous genetic abnormalities have been identified in acute lymphoblastic leukemia (ALL). Here we review the recurrent abnormalities with emphasis on those recently discovered, and discuss their association with chemotherapy resistance or sensitivity and with clinical response to therapy. Also, the role of genetic abnormalities in leukemogenesis and their potential as therapeutic targets will be discussed.

Citing Articles

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Liu X, Zou Y, Ruan M, Chang L, Chen X, Wang S Front Cell Infect Microbiol. 2020; 10:558799.

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Centrosome Aberration Frequency and Disease Association in B-Acute Lymphoblastic Leukemia.

Kerketta L, Ghosh K, Nadkarni A, Madkaikar M, Vundinti B In Vivo. 2017; 31(2):215-220.

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