Pathogenicity of Infectious Bronchitis Virus Isolates from Ontario Chickens

Overview

Journal Can J Vet Res

Specialty Veterinary Medicine

Date 2008 Dec 18

PMID 19086372

Citations 23

Authors

Helena Grgic

D Bruce Hunter

Peter Hunton

Eva Nagy

Affiliations

Soon will be listed here.

Abstract

Infectious bronchitis (IB) is one of the important viral diseases of chickens, and in spite of regular vaccination, IB is a continuous problem in Canadian poultry operations. In an earlier study using sentinel chickens we determined the incidence of infectious bronchitis virus (IBV) in Ontario commercial layer flocks. The objective of this study was to determine the pathogenicity of 5 nonvaccine-related IBV isolates recovered from the sentinel birds. The clinical signs, gross, and histological lesions in specific pathogen-free chickens indicated that all 5 isolates caused mild lesions in the respiratory tract. An important finding of this study was the significantly lower average daily weight gain among virus-inoculated groups of chickens during the acute phase of infection. Based on sequences of part of the S1 gene IBV-ON2, IBV-ON3, and IBV-ON5 formed a cluster and they were closely related to strain CU-82792. IBV-ON4 had 98.7% identity with the strain PA/1220/9, a nephropathogenic variant.

Citing Articles

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References

Lai M, Cavanagh D . The molecular biology of coronaviruses. Adv Virus Res. 1997; 48:1-100. PMC: 7130985. View

Ignjatovic J, Galli L . The S1 glycoprotein but not the N or M proteins of avian infectious bronchitis virus induces protection in vaccinated chickens. Arch Virol. 1994; 138(1-2):117-34. PMC: 7087189. DOI: 10.1007/BF01310043. View

Cavanagh D . Severe acute respiratory syndrome vaccine development: experiences of vaccination against avian infectious bronchitis coronavirus. Avian Pathol. 2003; 32(6):567-82. PMC: 7154303. DOI: 10.1080/03079450310001621198. View

Boltz D, Nakai M, Bahra J . Avian infectious bronchitis virus: a possible cause of reduced fertility in the rooster. Avian Dis. 2005; 48(4):909-15. DOI: 10.1637/7192-040808R1. View

Bochkov Y, Tosi G, Massi P, Drygin V . Phylogenetic analysis of partial S1 and N gene sequences of infectious bronchitis virus isolates from Italy revealed genetic diversity and recombination. Virus Genes. 2006; 35(1):65-71. PMC: 7088928. DOI: 10.1007/s11262-006-0037-0. View

Handberg K, Nielsen O, Pedersen M, Jorgensen P . Detection and strain differentiation of infectious bronchitis virus in tracheal tissues from experimentally infected chickens by reverse transcription-polymerase chain reaction. Comparison with an immunohistochemical technique. Avian Pathol. 2016; 28(4):327-35. DOI: 10.1080/03079459994579. View

Cavanagh D, Picault J, Gough R, Hess M, Mawditt K, Britton P . Variation in the spike protein of the 793/B type of infectious bronchitis virus, in the field and during alternate passage in chickens and embryonated eggs. Avian Pathol. 2005; 34(1):20-5. DOI: 10.1080/03079450400025414. View

Kusters J, Niesters H, Lenstra J, Horzinek M, van der Zeijst B . Phylogeny of antigenic variants of avian coronavirus IBV. Virology. 1989; 169(1):217-21. PMC: 7131080. DOI: 10.1016/0042-6822(89)90058-5. View

Gelb Jr J, Keeler Jr C, Nix W, Rosenberger J, Cloud S . Antigenic and S-1 genomic characterization of the Delaware variant serotype of infectious bronchitis virus. Avian Dis. 1997; 41(3):661-9. View

10.

Boursnell M, Brown T, Foulds I, Green P, Tomley F, Binns M . Completion of the sequence of the genome of the coronavirus avian infectious bronchitis virus. J Gen Virol. 1987; 68 ( Pt 1):57-77. DOI: 10.1099/0022-1317-68-1-57. View

11.

Kingham B, Keeler Jr C, Nix W, Ladman B, Gelb Jr J . Identification of avian infectious bronchitis virus by direct automated cycle sequencing of the S-1 gene. Avian Dis. 2000; 44(2):325-35. View

12.

Cavanagh D . Coronavirus avian infectious bronchitis virus. Vet Res. 2007; 38(2):281-97. DOI: 10.1051/vetres:2006055. View

13.

Ignjatovic J, Ashton D, Reece R, Scott P, Hooper P . Pathogenicity of Australian strains of avian infectious bronchitis virus. J Comp Pathol. 2002; 126(2-3):115-23. DOI: 10.1053/jcpa.2001.0528. View

14.

Sapats S, Ashton F, Wright P, Ignjatovic J . Sequence analysis of the S1 glycoprotein of infectious bronchitis viruses: identification of a novel genotypic group in Australia. J Gen Virol. 1996; 77 ( Pt 3):413-8. DOI: 10.1099/0022-1317-77-3-413. View

15.

Naqi S, Gay K, Patalla P, Mondal S, Liu R . Establishment of persistent avian infectious bronchitis virus infection in antibody-free and antibody-positive chickens. Avian Dis. 2003; 47(3):594-601. DOI: 10.1637/6087. View

16.

Jones R, Ambali A . Re-excretion of an enterotropic infectious bronchitis virus by hens at point of lay after experimental infection at day old. Vet Rec. 1987; 120(26):617-8. DOI: 10.1136/vr.120.26.617. View

17.

Nix W, Troeber D, Kingham B, Keeler Jr C, Gelb Jr J . Emergence of subtype strains of the Arkansas serotype of infectious bronchitis virus in Delmarva broiler chickens. Avian Dis. 2000; 44(3):568-81. View

18.

Albassam M, WINTERFIELD R, Thacker H . Comparison of the nephropathogenicity of four strains of infectious bronchitis virus. Avian Dis. 1986; 30(3):468-76. View

19.

Keeler Jr C, Reed K, Nix W, Gelb Jr J . Serotype identification of avian infectious bronchitis virus by RT-PCR of the peplomer (S-1) gene. Avian Dis. 1998; 42(2):275-84. View

20.

Cook J, Chesher J, Baxendale W, Greenwood N, Huggins M, Orbell S . Protection of chickens against renal damage caused by a nephropathogenic infectious bronchitis virus. Avian Pathol. 2009; 30(4):423-6. DOI: 10.1080/03079450120066421. View