Evaluation of Exercised or Cooled Skeletal Muscle on the Basis of Diffusion-weighted Magnetic Resonance Imaging

Overview

Journal Eur J Appl Physiol

Specialty Physiology

Date 2008 Dec 17

PMID 19084988

Citations 5

Authors

Osamu Yanagisawa

Daisuke Shimao

Katsuya Maruyama

Matthew Nielsen

Affiliations

Soon will be listed here.

Abstract

In this study, we assessed the physiological changes after exercising or cooling skeletal muscles on the basis of the apparent diffusion coefficient (ADC) values in magnetic resonance (MR) diffusion-weighted images (DWIs). DWIs of the ankle dorsiflexors were acquired with a 1.5-T MR device before and after exercising (22 subjects) or cooling (19 subjects). The exercise comprised a 5-min walk with the ankles dorsiflexed and a 30-time ankle dorsiflexion. Cooling (0 degrees C) of the ankle dorsiflexors was performed for 30 min. ADC values were calculated as ADC1-reflecting diffusion and perfusion and ADC2-approximating the true diffusion coefficient of the ankle dorsiflexors before and after exercising or cooling. ADC1 and ADC2 significantly increased with exercise and decreased with cooling (P < 0.05). Considering both diffusion and perfusion, ADC values allowed us to evaluate the intramuscular changes induced by exercising or cooling in terms of the motion of water molecules and microcirculation.

Citing Articles

Quantitative analysis of masticatory muscle changes by Eichner index using diffusion-weighted imaging.

Muraoka H, Kaneda T, Ito K, Hirahara N, Kondo T, Tokunaga S Oral Radiol. 2022; 39(2):437-445.

PMID: 36138256 DOI: 10.1007/s11282-022-00656-5.

Short- and long-term reproducibility of diffusion-weighted magnetic resonance imaging of lower extremity musculature in asymptomatic individuals and a comparison to individuals with spinal cord injury.

McPherson J, Smith A, Duben D, McMahon K, Wasielewski M, Parrish T BMC Musculoskelet Disord. 2018; 19(1):433.

PMID: 30522482 PMC: 6284280. DOI: 10.1186/s12891-018-2361-7.

Apparent Diffusion Coefficient Is a Novel Imaging Biomarker of Myopathic Changes in Liver Cirrhosis.

Surov A, Paul L, Meyer H, Schob S, Engelmann C, Wienke A J Clin Med. 2018; 7(10).

PMID: 30326652 PMC: 6210701. DOI: 10.3390/jcm7100359.

Advancements in Imaging Technology: Do They (or Will They) Equate to Advancements in Our Knowledge of Recovery in Whiplash?.

Elliott J, Dayanidhi S, Hazle C, Hoggarth M, McPherson J, Sparks C J Orthop Sports Phys Ther. 2016; 46(10):862-873.

PMID: 27690836 PMC: 7274526. DOI: 10.2519/jospt.2016.6735.

Diffusion-weighted Magnetic Resonance Imaging: What Makes Water Run Fast or Slow?.

Fornasa F J Clin Imaging Sci. 2011; 1:27.

PMID: 21966624 PMC: 3177415. DOI: 10.4103/2156-7514.81294.

References

Turner R, Le Bihan D, Maier J, Vavrek R, Hedges L, Pekar J . Echo-planar imaging of intravoxel incoherent motion. Radiology. 1990; 177(2):407-14. DOI: 10.1148/radiology.177.2.2217777. View

Yao L, Sinha U . Imaging the microcirculatory proton fraction of muscle with diffusion-weighted echo-planar imaging. Acad Radiol. 2000; 7(1):27-32. DOI: 10.1016/s1076-6332(00)80440-7. View

Le Rumeur E, De Certaines J, Toulouse P, Rochcongar P . Water phases in rat striated muscles as determined by T2 proton NMR relaxation times. Magn Reson Imaging. 1987; 5(4):267-72. DOI: 10.1016/0730-725x(87)90003-8. View

Fotedar L, Slopis J, Narayana P, Fenstermacher M, Pivarnik J, Butler I . Proton magnetic resonance of exercise-induced water changes in gastrocnemius muscle. J Appl Physiol (1985). 1990; 69(5):1695-701. DOI: 10.1152/jappl.1990.69.5.1695. View

Doran M, Bydder G . Magnetic resonance: perfusion and diffusion imaging. Neuroradiology. 1990; 32(5):392-8. DOI: 10.1007/BF00588472. View

Cagnie B, Dickx N, Peeters I, Tuytens J, Achten E, Cambier D . The use of functional MRI to evaluate cervical flexor activity during different cervical flexion exercises. J Appl Physiol (1985). 2007; 104(1):230-5. DOI: 10.1152/japplphysiol.00918.2007. View

Yanagisawa O, Homma T, Okuwaki T, Shimao D, Takahashi H . Effects of cooling on human skin and skeletal muscle. Eur J Appl Physiol. 2007; 100(6):737-45. DOI: 10.1007/s00421-007-0470-3. View

Yanagisawa O, Kudo H, Takahashi N, Yoshioka H . Magnetic resonance imaging evaluation of cooling on blood flow and oedema in skeletal muscles after exercise. Eur J Appl Physiol. 2004; 91(5-6):737-40. DOI: 10.1007/s00421-004-1060-2. View

Yanagisawa O, Shimao D, Maruyama K, Nielsen M, Irie T, Niitsu M . Diffusion-weighted magnetic resonance imaging of human skeletal muscles: gender-, age- and muscle-related differences in apparent diffusion coefficient. Magn Reson Imaging. 2008; 27(1):69-78. DOI: 10.1016/j.mri.2008.05.011. View

10.

Kenny G, Reardon F, ZALESKI W, Reardon M, Haman F, Ducharme M . Muscle temperature transients before, during, and after exercise measured using an intramuscular multisensor probe. J Appl Physiol (1985). 2003; 94(6):2350-7. DOI: 10.1152/japplphysiol.01107.2002. View

11.

Hiroyuki H, Hamaoka T, Sako T, Nishio S, Kime R, Murakami M . Oxygenation in vastus lateralis and lateral head of gastrocnemius during treadmill walking and running in humans. Eur J Appl Physiol. 2002; 87(4-5):343-9. DOI: 10.1007/s00421-002-0644-y. View

12.

Le Bihan D, Breton E, lAllemand D, Grenier P, Cabanis E, LAVAL-JEANTET M . MR imaging of intravoxel incoherent motions: application to diffusion and perfusion in neurologic disorders. Radiology. 1986; 161(2):401-7. DOI: 10.1148/radiology.161.2.3763909. View

13.

Morvan D . In vivo measurement of diffusion and pseudo-diffusion in skeletal muscle at rest and after exercise. Magn Reson Imaging. 1995; 13(2):193-9. DOI: 10.1016/0730-725x(94)00096-l. View

14.

Ploutz-Snyder L, Convertino V, Dudley G . Resistance exercise-induced fluid shifts: change in active muscle size and plasma volume. Am J Physiol. 1995; 269(3 Pt 2):R536-43. DOI: 10.1152/ajpregu.1995.269.3.R536. View

15.

Phuttharak W, Galassi W, Laopaiboon V, Laopaiboon M, Hesselink J . Abnormal diffusivity of normal appearing brain tissue in multiple sclerosis: a diffusion-weighted MR imaging study. J Med Assoc Thai. 2008; 90(12):2689-94. View

16.

Burdette J, Elster A, Ricci P . Acute cerebral infarction: quantification of spin-density and T2 shine-through phenomena on diffusion-weighted MR images. Radiology. 1999; 212(2):333-9. DOI: 10.1148/radiology.212.2.r99au36333. View

17.

Heemskerk A, Drost M, van Bochove G, van Oosterhout M, Nicolay K, Strijkers G . DTI-based assessment of ischemia-reperfusion in mouse skeletal muscle. Magn Reson Med. 2006; 56(2):272-81. DOI: 10.1002/mrm.20953. View

18.

Larsen R, Ringgaard S, Overgaard K . Localization and quantification of muscle damage by magnetic resonance imaging following step exercise in young women. Scand J Med Sci Sports. 2007; 17(1):76-83. DOI: 10.1111/j.1600-0838.2006.00525.x. View

19.

Sjogaard G, Saltin B . Extra- and intracellular water spaces in muscles of man at rest and with dynamic exercise. Am J Physiol. 1982; 243(3):R271-80. DOI: 10.1152/ajpregu.1982.243.3.R271. View

20.

Morvan D, Leroy-Willig A . Simultaneous measurements of diffusion and transverse relaxation in exercising skeletal muscle. Magn Reson Imaging. 1995; 13(7):943-8. DOI: 10.1016/0730-725x(95)02006-f. View