Effect of Rikkunshito, a Chinese Herbal Medicine, on Stasis in Patients After Pylorus-preserving Gastrectomy

Overview

Journal World J Surg

Publisher Wiley

Specialty General Surgery

Date 2008 Dec 17

PMID 19082653

Citations 21

Authors

Tsuyoshi Takahashi

Shunji Endo

Kiyokazu Nakajima

Yoshihito Souma

Toshirou Nishida

Affiliations

Soon will be listed here.

Abstract

Background: Distal gastrectomy (DG) and pylorus-preserving gastrectomy (PPG) have been employed for gastric cancer, with PPG having been reported to be superior to DG in regard to postoperative quality of life. Some patients with these operations still suffer from gastric stasis, however. In this study, we aimed to examine the clinical effects of rikkunshito on patients who were to undergo PPG.

Methods: A total of 11 patients who were scheduled to undergo PPG for early gastric cancer at the Osaka University Hospital were enrolled. The patients were randomly assigned to the crossover study with and without rikkunshito 7.5 g/day. Questionnaires and emptying tests using (111)In-labeled liquid scintigraphy and (99m)Tc-labeled solid scintigraphy were performed at the end of each treatment period.

Results: Stasis-related symptoms were significantly reduced during rikkunshito treatment (p = 0.043). The emptying test showed that rikkunshito improved emptying of solid meals (p = 0.0003) from the remnant stomach but did not accelerate gastric empting of liquid meals.

Conclusions: Rikkunshito improved gastric emptying and ameliorated postoperative symptoms of patients who had undergone a PPG.

Citing Articles

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Effect of Rikkunshito, a Traditional Japanese Herbal Medicine, on Delayed Gastric Emptying and Oral Dietary Intake After Pancreaticoduodenectomy: A Prospective, Randomized, Single-Center, Open-Labeled Study.

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Hong S, Park B, Noh H, Choi D Integr Cancer Ther. 2019; 18:1534735419873404.

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Benefit of Adjuvant Traditional Herbal Medicine With Chemotherapy for Resectable Gastric Cancer.

Lee Y, Bae K, Yoo H, Cho S Integr Cancer Ther. 2018; 17(3):619-627.

PMID: 29614889 PMC: 6142080. DOI: 10.1177/1534735417753542.

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