ER Stress and Lipogenesis: a Slippery Slope Toward Hepatic Steatosis

Overview

Journal Dev Cell

Publisher Cell Press

Specialties Cell Biology
Reproductive Medicine

Date 2008 Dec 17

PMID 19081067

Citations 22

Authors

Sana Basseri

Richard C Austin

Affiliations

Soon will be listed here.

Abstract

Endoplasmic reticulum (ER) stress and activation of the unfolded protein response have been linked to many human disorders, including obesity, type 2 diabetes, and cancer. In this issue of Developmental Cell,Rutkowski et al. (2008) show that unresolved ER stress contributes to metabolic dysfunction and hepatic steatosis.

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