Cardiac Regeneration and Stem Cell Therapy

Overview

Journal Curr Opin Organ Transplant

Specialty General Surgery

Date 2008 Dec 9

PMID 19060539

Citations 30

Authors

Joshua M Hare

Sandra V Chaparro

Affiliations

Soon will be listed here.

Abstract

Purpose Of Review: Significant recent developments have occurred in the field of cardiac regeneration and stem-cell therapy. Understanding the new technological advances in cell therapy will ultimate allow us to achieve a goal of cell-based cardiac repair.

Recent Findings: We discuss the latest cell-based therapies (including skeletal myoblasts, bone-marrow-derived cells, stem cells), the recent clinical trials in humans and different delivery techniques.

Summary: Ongoing unraveling of the mechanistic and clinical complexities underlying cardiac regeneration will advance the field of regenerative medicine. Substantial progress is being made by the parallel conduct of basic science studies and clinical trials that are incorporating mechanistic evaluations.

Citing Articles

Electrospun Fibers for Use in Implantable Materials to Support Cell Therapy.

Hernandez-Sanchez D, Spasojevic A, Suuronen E, Alarcon E Methods Mol Biol. 2024; 2835:289-300.

PMID: 39105924 DOI: 10.1007/978-1-0716-3995-5_24.

Unlocking the Mysteries, Bridging the Gap, and Unveiling the Multifaceted Potential of Stem Cell Therapy for Cardiac Tissue Regeneration: A Narrative Review of Current Literature, Ethical Challenges, and Future Perspectives.

Abubakar M, Masood M, Javed I, Adil H, Faraz M, Bhat R Cureus. 2023; 15(7):e41533.

PMID: 37551212 PMC: 10404462. DOI: 10.7759/cureus.41533.

Commentary: Evidence-based human stem cell therapy for myocardial healing: Miles to go.

Agrawal D, Thankam F JTCVS Open. 2022; 8:144-146.

PMID: 36004196 PMC: 9390384. DOI: 10.1016/j.xjon.2021.06.019.

Stem Cell-Derived Exosomes Potential Therapeutic Roles in Cardiovascular Diseases.

Jayaraman S, Gnanasampanthapandian D, Rajasingh J, Palaniyandi K Front Cardiovasc Med. 2021; 8:723236.

PMID: 34447796 PMC: 8382889. DOI: 10.3389/fcvm.2021.723236.

3D bioprinting of stem cell-laden cardiac patch: A promising alternative for myocardial repair.

Das S, Nam H, Jang J APL Bioeng. 2021; 5(3):031508.

PMID: 34368602 PMC: 8318604. DOI: 10.1063/5.0030353.

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