» Articles » PMID: 19059847

Adverse Childhood Events and Lifetime Alcohol Dependence

Overview
Specialty Public Health
Date 2008 Dec 9
PMID 19059847
Citations 94
Authors
Affiliations
Soon will be listed here.
Abstract

Objectives: We sought to study the association between adverse events occurring in childhood and adolescence and lifetime alcohol dependence in a representative sample of American adults.

Methods: With data from the National Epidemiologic Survey on Alcohol and Related Conditions, we conducted logistic regression multivariate analyses to examine the impact of adverse events occurring in childhood (aged < 18 years) on the lifetime prevalence of alcohol dependence. We controlled for age at drinking onset, binge drinking, alcoholism in parents and grandparents of respondents, and demographic characteristics.

Results: Adverse childhood events were associated with familial alcoholism and with early and binge drinking, and therefore, we controlled for these potential confounders. Experiencing 2 or more adverse childhood events, compared with none, significantly increased the risk for alcohol dependence, even after we controlled for sociodemographic variables and disorder-specific potential confounders not considered in the extant literature (adjusted odds ratio = 1.37; 95% confidence interval = 1.06, 1.77).

Conclusions: Individuals who experienced 2 or more adverse childhood events are at increased risk for lifetime alcohol dependence. A better understanding of the factors underlying the risk for alcohol dependence is important for developing better prevention and early intervention measures.

Citing Articles

Alcohol use among populations with autism spectrum disorder: narrative systematic review.

Barber W, Aslan B, Meynen T, Marsden J, Chamberlain S, Paleri V BJPsych Open. 2025; 11(1):e15.

PMID: 39801022 PMC: 11736162. DOI: 10.1192/bjo.2024.824.


Potentially traumatic events and the association with hazardous alcohol use in 19,128 middle aged and elderly adults: the Tromsø Study 2015-2016.

Husberg-Bru V, Hopstock L, Thimm J, Lid T, Rognmo K, Wang C Soc Psychiatry Psychiatr Epidemiol. 2024; .

PMID: 39692871 DOI: 10.1007/s00127-024-02801-3.


Does sex moderate the effects of early life stress on peripheral inflammation in alcohol use disorder? A preliminary investigation.

Kirsch D, Grodin E, Gillis A, Miotto K, Ray L Drug Alcohol Depend. 2024; 265:112474.

PMID: 39490200 PMC: 11824112. DOI: 10.1016/j.drugalcdep.2024.112474.


Alcohol Deprivation Differentially Changes Alcohol Intake in Female and Male Rats Depending on Early-Life Stressful Experience.

Carvalho M, Morais-Silva G, Caixeta G, Marin M, Amaral V NeuroSci. 2024; 3(2):214-225.

PMID: 39483372 PMC: 11523756. DOI: 10.3390/neurosci3020016.


Mixed-methods analysis of satisfaction during a 12-session mindfulness-based intervention for women with a substance use disorder and trauma symptomatology.

Bautista T, Ware O, Macias Burgos M, Rivas V, Cruz-Carrillo Y, Davidson A Front Psychol. 2024; 15:1359174.

PMID: 38939226 PMC: 11210173. DOI: 10.3389/fpsyg.2024.1359174.


References
1.
Kendler K, Heath A, Neale M, Kessler R, Eaves L . A population-based twin study of alcoholism in women. JAMA. 1992; 268(14):1877-82. View

2.
Grant B, Stinson F, Dawson D, Chou S, Dufour M, Compton W . Prevalence and co-occurrence of substance use disorders and independent mood and anxiety disorders: results from the National Epidemiologic Survey on Alcohol and Related Conditions. Arch Gen Psychiatry. 2004; 61(8):807-16. DOI: 10.1001/archpsyc.61.8.807. View

3.
Nelson C, Rehm J, Ustun T, Grant B, Chatterji S . Factor structures for DSM-IV substance disorder criteria endorsed by alcohol, cannabis, cocaine and opiate users: results from the WHO reliability and validity study. Addiction. 2000; 94(6):843-55. DOI: 10.1046/j.1360-0443.1999.9468438.x. View

4.
Andreasen N, Endicott J, Spitzer R, Winokur G . The family history method using diagnostic criteria. Reliability and validity. Arch Gen Psychiatry. 1977; 34(10):1229-35. DOI: 10.1001/archpsyc.1977.01770220111013. View

5.
Dube S, Miller J, Brown D, Giles W, Felitti V, Dong M . Adverse childhood experiences and the association with ever using alcohol and initiating alcohol use during adolescence. J Adolesc Health. 2006; 38(4):444.e1-10. DOI: 10.1016/j.jadohealth.2005.06.006. View