» Articles » PMID: 19050213

Genital Tract Infections Among HIV-infected Pregnant Women in Malawi, Tanzania and Zambia

Overview
Journal Int J STD AIDS
Date 2008 Dec 4
PMID 19050213
Citations 21
Authors
Affiliations
Soon will be listed here.
Abstract

The aim of this study was to compare the prevalence and factors associated with genital tract infections among HIV-infected pregnant women from African sites. Participants were recruited from Blantyre and Lilongwe, Malawi; Dar es Salaam, Tanzania; and Lusaka, Zambia. Genital tract infections were assessed at baseline. Of 2627 eligible women enrolled, 2292 were HIV-infected. Of these, 47.8% had bacterial vaginosis (BV), 22.4% had vaginal candidiasis, 18.8% had trichomoniasis, 8.5% had genital warts, 2.6% had chlamydia infection, 2.2% had genital ulcers and 1.7% had gonorrhoea. The main factors associated with genital tract infections included genital warts (adjusted odds ratio [AOR] 1.8, 95% CI 1.2-2.7), genital ulcers (AOR 2.4, 95% CI 1.2-5.1) and abnormal vaginal discharge (AOR 2.5, 95% CI 1.9-3.3) for trichomoniasis. BV was the most common genital tract infection followed by candidiasis and trichomoniasis. Differences in burdens and risk factors call for enhanced interventions for identification of genital tract infections among HIV-infected women.

Citing Articles

High rates of Treponema pallidum, Neisseria gonorrhoeae, Chlamydia trachomatis, or Trichomonas vaginalis co-infection in people with HIV: a systematic review and meta-analysis.

Zhang Q, Peng L, Yuan Y, Hu Z, Zeng Y, Zeng W Eur J Clin Microbiol Infect Dis. 2024; 44(1):1-15.

PMID: 39466544 DOI: 10.1007/s10096-024-04966-w.


Self-reported uptake of STI testing services among adolescents and young people aged 15-24 years: Findings from the Yathu Yathu cluster randomized trial in Lusaka, Zambia.

Hensen B, Phiri M, Sigande L, Schaap A, Simuyaba M, Zulu-Phiri R PLOS Glob Public Health. 2024; 4(3):e0002491.

PMID: 38437238 PMC: 10911628. DOI: 10.1371/journal.pgph.0002491.


A retrospective analysis of the trends in modern contraceptive use among adolescents and young women (15-24 years) in the Democratic Republic of the Congo in the last two decades.

Kaniki F, Sanni O, Kyampof K, Lazare S J Family Med Prim Care. 2023; 12(10):2260-2267.

PMID: 38074248 PMC: 10706545. DOI: 10.4103/jfmpc.jfmpc_128_23.


Bacterial vaginosis, the leading cause of genital discharge among women presenting with vaginal infection in Dar es Salaam, Tanzania.

Majigo M, Kashindye P, Mtulo Z, Joachim A Afr Health Sci. 2021; 21(2):531-537.

PMID: 34795705 PMC: 8568229. DOI: 10.4314/ahs.v21i2.7.


Predictors of Bacterial Vaginosis among Pregnant Women Attending Antenatal Clinic at Tertiary Care Hospital in Tanzania: A Cross Sectional Study.

Shaffi A, Balandya B, Majigo M, Aboud S East Afr Health Res J. 2021; 5(1):59-68.

PMID: 34308246 PMC: 8291208. DOI: 10.24248/eahrj.v5i1.652.


References
1.
Wessel H, Herrmann B, Dupret A, Moniz F, Brito C, Bergstrom S . Genital infections among antenatal care attendees in Cape Verde. Afr J Reprod Health. 1999; 2(1):32-40. View

2.
Buve A, Weiss H, Laga M, Van Dyck E, Musonda R, Zekeng L . The epidemiology of gonorrhoea, chlamydial infection and syphilis in four African cities. AIDS. 2001; 15 Suppl 4:S79-88. DOI: 10.1097/00002030-200108004-00009. View

3.
Taha T, Dallabetta G, Hoover D, Chiphangwi J, MTIMAVALYE L, Liomba G . Trends of HIV-1 and sexually transmitted diseases among pregnant and postpartum women in urban Malawi. AIDS. 1998; 12(2):197-203. DOI: 10.1097/00002030-199802000-00010. View

4.
Mayaud P, Cornelissen J, Todd J, Kaatano G, West B, Uledi E . Validation of a WHO algorithm with risk assessment for the clinical management of vaginal discharge in Mwanza, Tanzania. Sex Transm Infect. 1999; 74 Suppl 1:S77-84. View

5.
Sturm A, Wilkinson D, Ndovela N, Bowen S, Connolly C . Pregnant women as a reservoir of undetected sexually transmitted diseases in rural South Africa: implications for disease control. Am J Public Health. 1998; 88(8):1243-5. PMC: 1508306. DOI: 10.2105/ajph.88.8.1243. View