Leiomyosarcoma of the Prostate: Case Report and Review of 54 Previously Published Cases

Overview

Journal Sarcoma

Publisher Wiley

Date 2008 Dec 2

PMID 19043598

Citations 17

Authors

Gerasimos P Vandoros

Theodoros Manolidis

Michalis V Karamouzis

Maria Gkermpesi

Maria Lambropoulou

Athanasios G Papatsoris

Ioannis Zachos

Panagiotis A Konstantinopoulos

Affiliations

Soon will be listed here.

Abstract

Prostate leiomyosarcoma is an extremely rare and highly aggressive neoplasm that accounts for less than 0.1% of primary prostate malignancies. We present a patient with primary leiomyosarcoma of the prostate and review 54 cases reported in the literature to discuss the clinical, diagnostic and therapeutic aspects of this uncommon tumor. Median survival was estimated at 17 months (95% C.I. 20.7-43.7 months) and the 1-, 3-, and 5-year actuarial survival rates were 68%, 34%, and 26%, respectively. The only factors predictive of long-term survival were negative surgical margins and absence of metastatic disease at presentation. A multidisciplinary approach is necessary for appropriate management of this dire entity.

Citing Articles

Leiomyoma of the prostate: A case report and literature review.

Liu Z, Lu J, Yu K, Jian T, Hu R, Liu M Medicine (Baltimore). 2024; 103(44):e40340.

PMID: 39495968 PMC: 11537628. DOI: 10.1097/MD.0000000000040340.

Leiomyosarcoma of the Prostate: Report of Two Cases and Review of the Literature.

Bettaieb O, Keskes A, Llacer Moscardo C Case Rep Oncol. 2024; 17(1):454-462.

PMID: 38455715 PMC: 10919910. DOI: 10.1159/000535425.

Undifferentiated Sarcoma: A Rare Tumor of the Prostate.

Jaouani L, Zaimi A, Al Jarroudi O, Brahmi S, Afqir S Cureus. 2023; 15(6):e41056.

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Can pelvic radiotherapy induce a leiomyosarcoma of the prostate? (A case report).

Bkiri S, Tlemsani Z, Khdach Y, Bennani K, Abbad F, Ghadouane M Pan Afr Med J. 2022; 43:56.

PMID: 36578814 PMC: 9755551. DOI: 10.11604/pamj.2022.43.56.36997.

Long-term disease control after upfront chemotherapy and surgery in a patient with primary prostate leiomyosarcoma.

Kawaguchi T, Tanaka T, Ogasawara M, Ikuya I IJU Case Rep. 2022; 5(2):88-91.

PMID: 35252786 PMC: 8888012. DOI: 10.1002/iju5.12400.

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