A Grapevine (Vitis Vinifera L.) Deoxy-D: -xylulose Synthase Gene Colocates with a Major Quantitative Trait Loci for Terpenol Content

Overview

Journal Theor Appl Genet

Publisher Springer

Specialty Genetics

Date 2008 Nov 13

PMID 19002427

Citations 35

Authors

Eric Duchene

Gisele Butterlin

Patricia Claudel

Vincent Dumas

Nathalie Jaegli

Didier Merdinoglu

Affiliations

Soon will be listed here.

Abstract

Linalool, geraniol, nerol, citronellol and alpha-terpineol are isoprenoid molecules responsible for specific aromas found in grapes and wines. Total concentrations (free and bound forms) of these compounds were measured in the skins of mature berries during 2 successive years in two progenies obtained from Muscat Ottonel and Gewurztraminer selfings. Partial genetic maps based on microsatellite markers were constructed and several quantitative trait loci (QTLs) related to terpenol content were detected. A major QTL on linkage group (LG) 5 colocated with a deoxy-D: -xylulose synthase gene, coding for the first enzyme of the plastidial isoprenoid biosynthesis pathway. The number of favourable alleles at this locus determined the level of terpenol synthesis. A second QTL, on LG 10, was found to determine the balance linalool versus geraniol and nerol in the Muscat self-progeny plants.

Citing Articles

Combined sensory, volatilome and transcriptome analyses identify a limonene terpene synthase as a major contributor to the characteristic aroma of a Coffea arabica L. specialty coffee.

Marie L, Breitler J, Bamogo P, Bordeaux M, Lacombe S, Rios M BMC Plant Biol. 2024; 24(1):238.

PMID: 38566027 PMC: 10988958. DOI: 10.1186/s12870-024-04890-3.

Editing VvDXS1 for the creation of muscat flavour in Vitis vinifera cv. Scarlet Royal.

Yang Y, Wheatley M, Meakem V, Galarneau E, Gutierrez B, Zhong G Plant Biotechnol J. 2024; 22(6):1610-1621.

PMID: 38243882 PMC: 11123410. DOI: 10.1111/pbi.14290.

Berry texture QTL and candidate gene analysis in grape ( L.).

Lin H, Ma L, Guo Q, Liu C, Hou Y, Liu Z Hortic Res. 2023; 10(12):uhad226.

PMID: 38077492 PMC: 10709548. DOI: 10.1093/hr/uhad226.

Basic leucine zipper gene is expressed at a quantitative trait locus for high monoterpene content in grape berries.

Zhang Y, Liu C, Liu X, Wang Z, Wang Y, Zhong G Hortic Res. 2023; 10(9):uhad151.

PMID: 37701455 PMC: 10493639. DOI: 10.1093/hr/uhad151.

Transcription factors TgbHLH95 and TgbZIP44 cotarget terpene biosynthesis gene TgGPPS in Torreya grandis nuts.

Zhang Z, Tao L, Gao L, Gao Y, Suo J, Yu W Plant Physiol. 2023; 193(2):1161-1176.

PMID: 37399247 PMC: 10517253. DOI: 10.1093/plphys/kiad385.

References

Jaillon O, Aury J, Noel B, Policriti A, Clepet C, Casagrande A . The grapevine genome sequence suggests ancestral hexaploidization in major angiosperm phyla. Nature. 2007; 449(7161):463-7. DOI: 10.1038/nature06148. View

Adam-Blondon A, Roux C, Claux D, Butterlin G, Merdinoglu D, This P . Mapping 245 SSR markers on the Vitis vinifera genome: a tool for grape genetics. Theor Appl Genet. 2004; 109(5):1017-27. DOI: 10.1007/s00122-004-1704-y. View

Enfissi E, Fraser P, Lois L, Boronat A, Schuch W, Bramley P . Metabolic engineering of the mevalonate and non-mevalonate isopentenyl diphosphate-forming pathways for the production of health-promoting isoprenoids in tomato. Plant Biotechnol J. 2006; 3(1):17-27. DOI: 10.1111/j.1467-7652.2004.00091.x. View

ESTEVEZ J, Cantero A, Reindl A, Reichler S, Leon P . 1-Deoxy-D-xylulose-5-phosphate synthase, a limiting enzyme for plastidic isoprenoid biosynthesis in plants. J Biol Chem. 2001; 276(25):22901-9. DOI: 10.1074/jbc.M100854200. View

Carretero-Paulet L, Cairo A, Botella-Pavia P, Besumbes O, Campos N, Boronat A . Enhanced flux through the methylerythritol 4-phosphate pathway in Arabidopsis plants overexpressing deoxyxylulose 5-phosphate reductoisomerase. Plant Mol Biol. 2006; 62(4-5):683-95. DOI: 10.1007/s11103-006-9051-9. View

Yang T, Li J, Wang H, Zeng Y . A geraniol-synthase gene from Cinnamomum tenuipilum. Phytochemistry. 2005; 66(3):285-93. DOI: 10.1016/j.phytochem.2004.12.004. View

de Givry S, Bouchez M, Chabrier P, Milan D, Schiex T . CARHTA GENE: multipopulation integrated genetic and radiation hybrid mapping. Bioinformatics. 2004; 21(8):1703-4. DOI: 10.1093/bioinformatics/bti222. View

Aharoni A, Giri A, Verstappen F, Bertea C, Sevenier R, Sun Z . Gain and loss of fruit flavor compounds produced by wild and cultivated strawberry species. Plant Cell. 2004; 16(11):3110-31. PMC: 527202. DOI: 10.1105/tpc.104.023895. View

Pichersky E, Lewinsohn E, Croteau R . Purification and characterization of S-linalool synthase, an enzyme involved in the production of floral scent in Clarkia breweri. Arch Biochem Biophys. 1995; 316(2):803-7. DOI: 10.1006/abbi.1995.1107. View

10.

Munoz-Bertomeu J, Arrillaga I, Ros R, Segura J . Up-regulation of 1-deoxy-D-xylulose-5-phosphate synthase enhances production of essential oils in transgenic spike lavender. Plant Physiol. 2006; 142(3):890-900. PMC: 1630752. DOI: 10.1104/pp.106.086355. View

11.

Iijima Y, Gang D, Fridman E, Lewinsohn E, Pichersky E . Characterization of geraniol synthase from the peltate glands of sweet basil. Plant Physiol. 2003; 134(1):370-9. PMC: 316316. DOI: 10.1104/pp.103.032946. View

12.

Riaz S, Dangl G, Edwards K, Meredith C . A microsatellite marker based framework linkage map of Vitis vinifera L. Theor Appl Genet. 2003; 108(5):864-72. DOI: 10.1007/s00122-003-1488-5. View

13.

Phillips M, Walter M, Ralph S, Dabrowska P, Luck K, Uros E . Functional identification and differential expression of 1-deoxy-D-xylulose 5-phosphate synthase in induced terpenoid resin formation of Norway spruce (Picea abies). Plant Mol Biol. 2007; 65(3):243-57. DOI: 10.1007/s11103-007-9212-5. View

14.

Martin D, Bohlmann J . Identification of Vitis vinifera (-)-alpha-terpineol synthase by in silico screening of full-length cDNA ESTs and functional characterization of recombinant terpene synthase. Phytochemistry. 2004; 65(9):1223-9. DOI: 10.1016/j.phytochem.2004.03.018. View

15.

Iijima Y, Davidovich-Rikanati R, Fridman E, Gang D, Bar E, Lewinsohn E . The biochemical and molecular basis for the divergent patterns in the biosynthesis of terpenes and phenylpropenes in the peltate glands of three cultivars of basil. Plant Physiol. 2004; 136(3):3724-36. PMC: 527170. DOI: 10.1104/pp.104.051318. View

16.

Velasco R, Zharkikh A, Troggio M, Cartwright D, Cestaro A, Pruss D . A high quality draft consensus sequence of the genome of a heterozygous grapevine variety. PLoS One. 2007; 2(12):e1326. PMC: 2147077. DOI: 10.1371/journal.pone.0001326. View

17.

Walter M, Hans J, Strack D . Two distantly related genes encoding 1-deoxy-d-xylulose 5-phosphate synthases: differential regulation in shoots and apocarotenoid-accumulating mycorrhizal roots. Plant J. 2002; 31(3):243-54. DOI: 10.1046/j.1365-313x.2002.01352.x. View

18.

Kim B, Kim S, Chang Y . Differential expression of three 1-deoxy-D: -xylulose-5-phosphate synthase genes in rice. Biotechnol Lett. 2005; 27(14):997-1001. DOI: 10.1007/s10529-005-7849-1. View

19.

Doligez A, Adam-Blondon A, Cipriani G, Di Gaspero G, Laucou V, Merdinoglu D . An integrated SSR map of grapevine based on five mapping populations. Theor Appl Genet. 2006; 113(3):369-82. DOI: 10.1007/s00122-006-0295-1. View

20.

Mahmoud S, Croteau R . Strategies for transgenic manipulation of monoterpene biosynthesis in plants. Trends Plant Sci. 2002; 7(8):366-73. DOI: 10.1016/s1360-1385(02)02303-8. View