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Heterogeneity of Embryonic and Adult Stem Cells

Overview
Journal Cell Stem Cell
Publisher Cell Press
Specialty Cell Biology
Date 2008 Nov 6
PMID 18983963
Citations 155
Authors
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Abstract

New studies suggest that stem cells of embryonic, neural, and hematopoietic origin are heterogeneous, with cells moving between two or more metastable states. These cell states show a bias in their differentiation potential and correlate with specific patterns of transcription factor expression and chromatin modifications.

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