A Novel L-amino Acid Ligase from Bacillus Licheniformis

Overview

Journal J Biosci Bioeng

Specialties Biochemistry
Biomedical Engineering
Microbiology

Date 2008 Oct 22

PMID 18930013

Citations 9

Authors

Kuniki Kino

Atsushi Noguchi

Yuji Nakazawa

Makoto Yagasaki

Affiliations

Soon will be listed here.

Abstract

l-Amino acid alpha-ligase (EC 6.3.2.28) catalyzed formation of alpha-peptide bond in unprotected l-amino acids in an ATP-dependent manner. BL00235 gene in Bacillus licheniformis NBRC12200 coded as a new l-amino acid ligase. BL00235 substrate specificity was strict; only methionine or leucine was acceptable as dipeptide N-terminal residues.

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