Acne Vulgaris, Mental Health and Omega-3 Fatty Acids: a Report of Cases
Overview
Endocrinology
Authors
Affiliations
Acne vulgaris is a common skin condition, one that is associated with significant psychological disability. The psychological impairments in acne include higher rates of depression, anxiety, anger and suicidal thoughts. Despite a paucity of clinical research, patients with skin conditions and/or mental health disorders are frequent consumers of dietary supplements. An overlap may exist between nutrients that potentially have both anti-acne and mood regulating properties; examples include omega-3 fatty acids from fish oil, chromium, zinc and selenium. Here we report on five cases of acne treated with eicosapentaenoic acid and antioxidant nutrients. Self-administration of these nutrients may have improved inflammatory acne lesions and global aspects of well-being; the observations suggest a need for controlled trials.
Deficit of Omega-3 Fatty Acids in Acne Patients-A Cross-Sectional Pilot Study in a German Cohort.
Guertler A, Fiedler T, Lill D, Kuna A, Volsky A, Wallmichrath J Life (Basel). 2024; 14(4).
PMID: 38672789 PMC: 11050840. DOI: 10.3390/life14040519.
Omega-6 highly unsaturated fatty acids in Leydig cells facilitate male sex hormone production.
Ri K, Lee-Okada H, Yokomizo T Commun Biol. 2022; 5(1):1001.
PMID: 36131086 PMC: 9492697. DOI: 10.1038/s42003-022-03972-y.
Al-Shahed F, Shoeb H, El-Shawwa M J Cell Mol Med. 2022; 26(20):5213-5221.
PMID: 36098243 PMC: 9575098. DOI: 10.1111/jcmm.17546.
Balic A, Vlasic D, Zuzul K, Marinovic B, Bukvic Mokos Z Int J Mol Sci. 2020; 21(3).
PMID: 31979308 PMC: 7037798. DOI: 10.3390/ijms21030741.
Synchronizing Pharmacotherapy in Acne with Review of Clinical Care.
Sacchidanand S, Lahiri K, Godse K, Patwardhan N, Ganjoo A, Kharkar R Indian J Dermatol. 2017; 62(4):341-357.
PMID: 28794543 PMC: 5527713. DOI: 10.4103/ijd.IJD_41_17.