Metabolic Programming in Pregnancy: Studies in Animal Models

Overview

Journal Genes Nutr

Publisher Biomed Central

Date 2008 Oct 14

PMID 18850136

Citations 12

Authors

S C Langley-Evans

Affiliations

Soon will be listed here.

Citing Articles

Maternal epigenetic clocks measured during pregnancy do not predict gestational age at delivery or offspring birth outcomes: a replication study in metropolitan Cebu, Philippines.

Ryan C, Rege R, Lee N, Carba D, Kobor M, MacIsaac J Clin Epigenetics. 2022; 14(1):78.

PMID: 35733189 PMC: 9219190. DOI: 10.1186/s13148-022-01296-6.

The children of Superstorm Sandy: Maternal prenatal depression blunts offspring electrodermal activity.

Buthmann J, Finik J, Ventura G, Zhang W, Shereen A, Nomura Y Biol Psychol. 2019; 146:107716.

PMID: 31176750 PMC: 6718305. DOI: 10.1016/j.biopsycho.2019.107716.

Infant Temperament: Repercussions of Superstorm Sandy-Related Maternal Stress.

Buthmann J, Ham J, Davey K, Finik J, Dana K, Pehme P Child Psychiatry Hum Dev. 2018; 50(1):150-162.

PMID: 30030653 PMC: 6339835. DOI: 10.1007/s10578-018-0828-2.

Hypothalamic oxidative stress and inflammation, and peripheral glucose homeostasis in Sprague-Dawley rat offspring exposed to maternal and postnatal chocolate and soft drink.

Kjaergaard M, Nilsson C, Nielsen M, Grove K, Raun K Nutr Diabetes. 2018; 8(1):44.

PMID: 30026488 PMC: 6053394. DOI: 10.1038/s41387-018-0051-z.

Differential hypothalamic leptin sensitivity in obese rat offspring exposed to maternal and postnatal intake of chocolate and soft drink.

Kjaergaard M, Nilsson C, Secher A, Kildegaard J, Skovgaard T, Nielsen M Nutr Diabetes. 2017; 7(1):e242.

PMID: 28092346 PMC: 5301042. DOI: 10.1038/nutd.2016.53.

References

Bellinger L, Sculley D, Langley-Evans S . Exposure to undernutrition in fetal life determines fat distribution, locomotor activity and food intake in ageing rats. Int J Obes (Lond). 2006; 30(5):729-38. PMC: 1865484. DOI: 10.1038/sj.ijo.0803205. View

Ravelli A, van der Meulen J, Osmond C, Barker D, Bleker O . Obesity at the age of 50 y in men and women exposed to famine prenatally. Am J Clin Nutr. 1999; 70(5):811-6. DOI: 10.1093/ajcn/70.5.811. View

McMillen I, Robinson J . Developmental origins of the metabolic syndrome: prediction, plasticity, and programming. Physiol Rev. 2005; 85(2):571-633. DOI: 10.1152/physrev.00053.2003. View

Kalies H, Heinrich J, Borte N, Schaaf B, von Berg A, von Kries R . The effect of breastfeeding on weight gain in infants: results of a birth cohort study. Eur J Med Res. 2005; 10(1):36-42. View

Taylor P, McConnell J, Khan I, Holemans K, Lawrence K, Asare-Anane H . Impaired glucose homeostasis and mitochondrial abnormalities in offspring of rats fed a fat-rich diet in pregnancy. Am J Physiol Regul Integr Comp Physiol. 2004; 288(1):R134-9. DOI: 10.1152/ajpregu.00355.2004. View

McMullen S, Langley-Evans S . Maternal low-protein diet in rat pregnancy programs blood pressure through sex-specific mechanisms. Am J Physiol Regul Integr Comp Physiol. 2004; 288(1):R85-90. DOI: 10.1152/ajpregu.00435.2004. View

Langley-Evans S, Welham S, Jackson A . Fetal exposure to a maternal low protein diet impairs nephrogenesis and promotes hypertension in the rat. Life Sci. 1999; 64(11):965-74. DOI: 10.1016/s0024-3205(99)00022-3. View

Langley-Evans S . Maternal carbenoxolone treatment lowers birthweight and induces hypertension in the offspring of rats fed a protein-replete diet. Clin Sci (Lond). 1998; 93(5):423-9. DOI: 10.1042/cs0930423. View

Groot P, van Vlijmen B, Benson G, Hofker M, Schiffelers R, Vidgeon-Hart M . Quantitative assessment of aortic atherosclerosis in APOE*3 Leiden transgenic mice and its relationship to serum cholesterol exposure. Arterioscler Thromb Vasc Biol. 1996; 16(8):926-33. DOI: 10.1161/01.atv.16.8.926. View

10.

Langley-Evans S . Hypertension induced by foetal exposure to a maternal low-protein diet, in the rat, is prevented by pharmacological blockade of maternal glucocorticoid synthesis. J Hypertens. 1997; 15(5):537-44. DOI: 10.1097/00004872-199715050-00010. View

11.

Woodall S, Johnston B, Breier B, Gluckman P . Chronic maternal undernutrition in the rat leads to delayed postnatal growth and elevated blood pressure of offspring. Pediatr Res. 1996; 40(3):438-43. DOI: 10.1203/00006450-199609000-00012. View

12.

Langley-Evans S, Phillips G, Benediktsson R, Gardner D, Edwards C, Jackson A . Protein intake in pregnancy, placental glucocorticoid metabolism and the programming of hypertension in the rat. Placenta. 1996; 17(2-3):169-72. DOI: 10.1016/s0143-4004(96)80010-5. View

13.

Langley S, Jackson A . Increased systolic blood pressure in adult rats induced by fetal exposure to maternal low protein diets. Clin Sci (Lond). 1994; 86(2):217-22; discussion 121. DOI: 10.1042/cs0860217. View

14.

Plagemann A, Heidrich I, Gotz F, Rohde W, Dorner G . Obesity and enhanced diabetes and cardiovascular risk in adult rats due to early postnatal overfeeding. Exp Clin Endocrinol. 1992; 99(3):154-8. DOI: 10.1055/s-0029-1211159. View

15.

Beach R, Gershwin M, Hurley L . Gestational zinc deprivation in mice: persistence of immunodeficiency for three generations. Science. 1982; 218(4571):469-71. DOI: 10.1126/science.7123244. View

16.

Jones A, Friedman M . Obesity and adipocyte abnormalities in offspring of rats undernourished during pregnancy. Science. 1982; 215(4539):1518-9. DOI: 10.1126/science.7063860. View

17.

Bellinger L, Lilley C, Langley-Evans S . Prenatal exposure to a maternal low-protein diet programmes a preference for high-fat foods in the young adult rat. Br J Nutr. 2004; 92(3):513-20. DOI: 10.1079/bjn20041224. View

18.

McMullen S, Osgerby J, Thurston L, Gadd T, Wood P, Wathes D . Alterations in placental 11 beta-hydroxysteroid dehydrogenase (11 betaHSD) activities and fetal cortisol:cortisone ratios induced by nutritional restriction prior to conception and at defined stages of gestation in ewes. Reproduction. 2004; 127(6):717-25. DOI: 10.1530/rep.1.00070. View

19.

Gopalakrishnan G, Gardner D, Rhind S, Rae M, Kyle C, Brooks A . Programming of adult cardiovascular function after early maternal undernutrition in sheep. Am J Physiol Regul Integr Comp Physiol. 2004; 287(1):R12-20. DOI: 10.1152/ajpregu.00687.2003. View

20.

Brawley L, Torrens C, Anthony F, Itoh S, Wheeler T, Jackson A . Glycine rectifies vascular dysfunction induced by dietary protein imbalance during pregnancy. J Physiol. 2003; 554(Pt 2):497-504. PMC: 1664758. DOI: 10.1113/jphysiol.2003.052068. View