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Effects of Diet on Glucose Control in Cats with Diabetes Mellitus Treated with Twice Daily Insulin Glargine

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Date 2008 Oct 7
PMID 18835801
Citations 12
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Abstract

The purpose of this study was to evaluate the effects of dietary modification in addition to twice daily insulin glargine. Cats were treated with insulin glargine twice daily and randomized to receive either a low carbohydrate, high protein (LCHP) diet (n=6) or a control diet (n=6) for 10 weeks. Re-evaluations of clinical signs, blood glucose curves, and serum fructosamine concentrations were performed at weeks 1, 2, 4, 6, and 10. Two of 12 cats achieved complete remission by the end of the study but remission rate was not different between diet groups. Using twice daily insulin glargine and frequent monitoring, all cats in both diet groups achieved successful glycemic control. Frequent monitoring is key to achieving glycemic control in diabetic cats; potential benefits of dietary modification require further evaluation.

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References
1.
Jenkins D, Ghafari H, Wolever T, Taylor R, Jenkins A, BARKER H . Relationship between rate of digestion of foods and post-prandial glycaemia. Diabetologia. 1982; 22(6):450-5. DOI: 10.1007/BF00282589. View

2.
Ihle S . Nutritional therapy for diabetes mellitus. Vet Clin North Am Small Anim Pract. 1995; 25(3):585-97. DOI: 10.1016/s0195-5616(95)50055-5. View

3.
Hoenig M, Thomaseth K, Brandao J, Waldron M, Ferguson D . Assessment and mathematical modeling of glucose turnover and insulin sensitivity in lean and obese cats. Domest Anim Endocrinol. 2006; 31(4):373-89. DOI: 10.1016/j.domaniend.2005.12.004. View

4.
Kimmel S, Michel K, Hess R, Ward C . Effects of insoluble and soluble dietary fiber on glycemic control in dogs with naturally occurring insulin-dependent diabetes mellitus. J Am Vet Med Assoc. 2000; 216(7):1076-81. DOI: 10.2460/javma.2000.216.1076. View

5.
Bennett N, Greco D, Peterson M, Kirk C, Mathes M, Fettman M . Comparison of a low carbohydrate-low fiber diet and a moderate carbohydrate-high fiber diet in the management of feline diabetes mellitus. J Feline Med Surg. 2005; 8(2):73-84. PMC: 10832676. DOI: 10.1016/j.jfms.2005.08.004. View