Asymmetric Hydrogenation of Cyclic Imines with an Ionic Cp*Rh(III) Catalyst

Overview

Journal J Am Chem Soc

Publisher American Chemical Society

Specialty Chemistry

Date 2008 Sep 12

PMID 18783215

Citations 13

Authors

Chaoqun Li

Jianliang Xiao

Affiliations

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Abstract

When associated with a noncoordinating bulky counteranion, a cationic Cp*Rh(III)-diamine catalyst displayed excellent enantioselectivities in asymmetric hydrogenation of cyclic imines, affording bioactive tetrahydroisoquinolines and tetrahydro-beta-carbolines frequently with 99% ee's.

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