The Accuracy of Sentinel Lymph Node Biopsy in the Treatment of Multicentric Invasive Breast Cancer Using a Subareolar Injection of Tracer

Overview

Journal World J Surg

Publisher Wiley

Specialty General Surgery

Date 2008 Aug 30

PMID 18726647

Citations 4

Authors

Calogero Cipolla

Salvatore Vieni

Salvatore Fricano

Daniela Cabibi

Giuseppa Graceffa

Renato Costa

Stefania Latteri

Mario A Latteri

Affiliations

Soon will be listed here.

Abstract

Background: The aim of this study was to evaluate the feasibility and the accuracy of sentinel lymph node biopsy in multicentric breast cancer (MBC) performed by means of a subareolar (SA) injection of both 99Tc-labeled human albumin colloid and lymphazurin.

Methods: Between January 2002 and October 2007, 34 patients with MBC with clinically negative axilla underwent sentinel lymph node biopsy (SLNB) followed by total axillary node dissection (AD). Overall successful identification rate of SLN was 100%; there were no false negatives and overall accuracy rate was 100%.

Results: The mean number of sentinel lymph nodes (SLNs) identified was 1.8 +/- 0.88 (range = 1-4); the mean number of axillary lymph nodes examined was 21.4 +/- 5.76 (range = 8-36).

Conclusions: The authors conclude that SA injection of the tracer is feasible and efficacious in the identification of the SLN. The accuracy of SLNB in MBC is comparable to that obtained in unifocal disease.

Citing Articles

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Effects of the number of removed lymph nodes on survival outcome in patients with sentinel node-negative breast cancer.

Cipolla C, Galvano A, Vieni S, Saputo F, Lupo S, Latteri M World J Surg Oncol. 2021; 19(1):306.

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