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Late Diagnosed Necrotizing Fasciitis As a Cause of Multiorgan Dysfunction Syndrome: A Case Report

Overview
Journal Cases J
Specialty General Medicine
Date 2008 Aug 30
PMID 18721475
Citations 3
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Abstract

Necrotizing fasciitis is a rapidly progressive, life-threatening soft tissue bacterial infection. We present a serious case of a 43-year-old male who suffered from necrotizing fasciitis of the left leg in whom a delayed diagnosis caused multiorgan dysfunction.Early recognition of important symptoms is essential in the management and surgical debridement of necrotizing fasciitis. Treatment should include comprehensive supportive measures (early goal-directed therapy, adequate ventilation strategy, activated protein C dosage, tight glucose control, steroids, renal replacement therapy) and early antibiotic therapy based on microbiologic monitoring. The pathophysiology and etiologic factors of necrotizing fasciitis are discussed.

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References
1.
Hashimoto N, Sugiyama H, Asagoe K, Hara K, Yamasaki O, Yamasaki Y . Fulminant necrotising fasciitis developing during long term corticosteroid treatment of systemic lupus erythematosus. Ann Rheum Dis. 2002; 61(9):848-9. PMC: 1754225. DOI: 10.1136/ard.61.9.848. View

2.
Cornia P, Davidson H, Lipsky B . The evaluation and treatment of complicated skin and skin structure infections. Expert Opin Pharmacother. 2008; 9(5):717-30. DOI: 10.1517/14656566.9.5.717. View

3.
Sendi P, Johansson L, Norrby-Teglund A . Invasive group B Streptococcal disease in non-pregnant adults : a review with emphasis on skin and soft-tissue infections. Infection. 2008; 36(2):100-11. DOI: 10.1007/s15010-007-7251-0. View

4.
Stevens D . Streptococcal toxic shock syndrome associated with necrotizing fasciitis. Annu Rev Med. 2000; 51:271-88. DOI: 10.1146/annurev.med.51.1.271. View

5.
Eriksson B, Andersson J, Holm S, Norgren M . Epidemiological and clinical aspects of invasive group A streptococcal infections and the streptococcal toxic shock syndrome. Clin Infect Dis. 1998; 27(6):1428-36. DOI: 10.1086/515012. View