A Case Report of Propofol Dependence in a Physician

Overview

Journal J Psychoactive Drugs

Specialties Pharmacology
Psychiatry

Date 2008 Aug 30

PMID 18720673

Citations 4

Authors

Udo Bonnet

Jorg Harkener

Norbert Scherbaum

Affiliations

Soon will be listed here.

Abstract

Propofol is a widely used general anaesthetic with multisite mechanisms and especially ultrashort activation of certain central GABA-A receptors. Since its introduction into the market in the mid 1980s this is the seventh report on propofol dependence in the literature. The present case shows for the first time that craving for propofol can be quite intense and able to induce addictive behaviour.

Citing Articles

Propofol misuse in medical professions: a scoping review.

Burnett G, Taree A, Martin L, Bryson E Can J Anaesth. 2022; 70(3):395-405.

PMID: 36577890 DOI: 10.1007/s12630-022-02382-2.

Extracellular Signal-Regulated Kinase in Nucleus Accumbens Mediates Propofol Self-Administration in Rats.

Wang B, Yang X, Sun A, Xu L, Wang S, Lin W Neurosci Bull. 2016; 32(6):531-537.

PMID: 27783327 PMC: 5567483. DOI: 10.1007/s12264-016-0066-1.

Clinical and psychological characteristics of propofol abusers in Korea: a survey of propofol abuse in 38, non-healthcare professionals.

Kim E, Kim S, Hyun Y, Noh Y, Jung H, Han S Korean J Anesthesiol. 2015; 68(6):586-93.

PMID: 26634083 PMC: 4667145. DOI: 10.4097/kjae.2015.68.6.586.

The misuse and abuse of propofol.

Monroe T, Hamza H, Stocks G, Scimeca P, Cowan R Subst Use Misuse. 2011; 46(9):1199-205.

PMID: 21463203 PMC: 6392060. DOI: 10.3109/10826084.2011.564705.