Acute Generalized Exanthematous Pustulosis After Pemetrexed, and Recurrence After Re-introduction

Overview

Journal Clin Exp Dermatol

Publisher Oxford University Press

Specialty Dermatology

Date 2008 Aug 14

PMID 18699838

Citations 3

Authors

A Bracke

E Van Marck

J Lambert

Affiliations

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Abstract

Acute generalized exanthematous pustulosis (AGEP) is a rare cutaneous reaction, which in most cases, is related to medication. Pemetrexed is an antifolate drug, approved for treatment of metastatic non-small-cell lung cancer (NSCLC) and malignant pleural mesothelioma (MPM). We present a case of AGEP caused by pemetrexed, and a recurrence of this eruption after re-introduction of pemetrexed despite use of corticosteroids.

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