Factors Associated with Functional Disability in Patients with Rheumatoid Arthritis

Overview

Journal Rheumatol Int

Specialty Rheumatology

Date 2008 Aug 13

PMID 18696072

Citations 11

Authors

Oznur Oken

Guzide Batur

Rukiye Gunduz

Rezan Z Yorgancioglu

Affiliations

Soon will be listed here.

Abstract

To determine factors associated with functional disability in patients with rheumatoid arthritis (RA). A total of 100 RA patients were reviewed retrospectively. Multiple regression analysis was used to investigate associations between the dependent variable (health assessment questionnaire) and independent variables (age, disease duration, hand grip strength values, VAS and DAS-28 scores). Main factors associated with functional disability were disease activity score as reflected in a high score on the DAS-28 (r=0.68, p<0.001) and disease duration (r=0.23, p<0.05). Increased age, decreased grip strength and high pain level were associated with lower functional ability, but none of these was a predictor of disability in the regression model. The results indicate that age, disease duration, disease activity, pain intensity and hand grip strength are related to physical disability in patients with RA. However, only disease activity has an impact on physical function. Thus, treatment of RA patients should focus on early inhibition of disease activity in order to achieve a good functional outcome.

Citing Articles

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