Mechanisms by Which Diabetes Increases Cardiovascular Disease

Overview

Journal Drug Discov Today Dis Mech

Publisher Elsevier

Date 2008 Aug 13

PMID 18695749

Citations 31

Authors

Christian A Gleissner

Elena Galkina

Jerry L Nadler

Klaus Ley

Affiliations

Soon will be listed here.

Abstract

Diabetes mellitus is one of the major risk factors for cardiovascular disease which is the leading cause of death in the U.S. Increasing prevalence of diabetes and diabetic atherosclerosis makes identification of molecular mechanisms by which diabetes promotes atherogenesis an important task. Targeting common pathways may ameliorate both diseases. This review focuses on well known as well as newly discovered mechanisms which may represent promising therapeutic targets.

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