Human Brain White Matter Atlas: Identification and Assignment of Common Anatomical Structures in Superficial White Matter

Overview

Journal Neuroimage

Specialty Radiology

Date 2008 Aug 12

PMID 18692144

Citations 274

Authors

Kenichi Oishi

Karl Zilles

Katrin Amunts

Andreia Faria

Hangyi Jiang

Xin Li

Kazi Akhter

Kegang Hua

Roger Woods

Arthur W Toga

G Bruce Pike

Pedro Rosa-Neto

Alan Evans

Jiangyang Zhang

Hao Huang

Michael I Miller

Peter C M van Zijl

John Mazziotta

Susumu Mori

Affiliations

Soon will be listed here.

Abstract

Structural delineation and assignment are the fundamental steps in understanding the anatomy of the human brain. The white matter has been structurally defined in the past only at its core regions (deep white matter). However, the most peripheral white matter areas, which are interleaved between the cortex and the deep white matter, have lacked clear anatomical definitions and parcellations. We used axonal fiber alignment information from diffusion tensor imaging (DTI) to delineate the peripheral white matter, and investigated its relationship with the cortex and the deep white matter. Using DTI data from 81 healthy subjects, we identified nine common, blade-like anatomical regions, which were further parcellated into 21 subregions based on the cortical anatomy. Four short association fiber tracts connecting adjacent gyri (U-fibers) were also identified reproducibly among the healthy population. We anticipate that this atlas will be useful resource for atlas-based white matter anatomical studies.

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