Gastric Ulcer and Gastritis

Overview

Journal Gut

Specialty Gastroenterology

Date 1971 Aug 1

PMID 18668833

Citations 32

Authors

M W Gear

S C TRUELOVE

R Whitehead

Affiliations

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Abstract

The gastritis associated with chronic gastric ulcer has been studied by means of biopsy specimens taken under vision through a fibreoptic gastroscope from four standard sites in the stomach. Observations have been made in patients with untreated gastric ulcer and also in patients after medical or surgical treatment of the ulcer. The gastritis is usually widespread in chronic peptic ulcer of the body of the stomach, whereas it is commonly more localized in chronic prepyloric ulcer. Superficial or atrophic gastritis has been found to persist or even worsen after healing of the ulcer, whether the treatment was medical or surgical. This finding suggests that gastritis is the basic disease process and that gastric ulceration is a secondary phenomenon.

Citing Articles

Link between Helicobacter pylori-associated gastritis and duodenal ulcer.

Saita H, Murakami M, Yoo J, Teramura S, Dekigai H, Takahashi Y Dig Dis Sci. 1993; 38(1):117-22.

PMID: 8420742 DOI: 10.1007/BF01296782.

Distribution of Helicobacter pylori colonisation and associated gastric inflammatory changes: difference between patients with duodenal and gastric ulcers.

Louw J, Falck V, Van Rensburg C, Zak J, Adams G, Marks I J Clin Pathol. 1993; 46(8):754-6.

PMID: 8408703 PMC: 501464. DOI: 10.1136/jcp.46.8.754.

Histological assessment of the Sydney classification of endoscopic gastritis.

Khakoo S, Lobo A, Shepherd N, Wilkinson S Gut. 1994; 35(9):1172-5.

PMID: 7959220 PMC: 1375689. DOI: 10.1136/gut.35.9.1172.

Pathophysiological effects of long-term acid suppression in man.

McCloy R, Arnold R, Bardhan K, Cattan D, Maton P, Riddell R Dig Dis Sci. 1995; 40(2 Suppl):96S-120S.

PMID: 7859587 DOI: 10.1007/BF02214874.

Are gastric and duodenal ulcers separate diseases or do they form a continuum?.

Kirk R Dig Dis Sci. 1981; 26(2):149-54.

PMID: 7460717 DOI: 10.1007/BF01312235.

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