Are Oppositional-defiant and Hyperactive-inattentive Symptoms Developmental Precursors to Conduct Problems in Late Childhood?: Genetic and Environmental Links

Overview

Journal J Abnorm Child Psychol

Publisher Springer

Date 2008 Jul 24

PMID 18648930

Citations 15

Authors

Benjamin B Lahey

Carol A Van Hulle

Paul J Rathouz

Joseph Lee Rodgers

Brian M DOnofrio

Irwin D Waldman

Affiliations

Soon will be listed here.

Abstract

Inattentive-hyperactive and oppositional behavior have been hypothesized to be developmental precursors to conduct problems. We tested these hypotheses using a longitudinal sample of 6,466 offspring of women selected from nationally representative US households. Conduct problems across 8-13 years were robustly predicted by conduct problems at 4-7 years, but also were independently predicted to a small extent by both inattentive-hyperactive and oppositional behaviors at 4-7 years. Longitudinal multivariate behavior genetic analyses revealed that the genetic and environmental factors that influence conduct problems at both 4-7 and 8-13 years also influence the putative precursors at 4-7 years. After genetic and environmental influences on conduct problems at 4-7 years were taken into account, however, inattentive-hyperactive and oppositional behavior at 4-7 years shared causal influences with conduct problems 8-13 years to a negligible extent. These findings suggest that after early conduct problems are controlled, little is gained in terms of prediction or understanding genetic and environmental influences on later child conduct problems by treating early inattentive-hyperactive and oppositional behavior as developmental precursors to later conduct problems.

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References

Zeger S, Liang K . Longitudinal data analysis for discrete and continuous outcomes. Biometrics. 1986; 42(1):121-30. View

Loeber R, Green S, Keenan K, Lahey B . Which boys will fare worse? Early predictors of the onset of conduct disorder in a six-year longitudinal study. J Am Acad Child Adolesc Psychiatry. 1995; 34(4):499-509. View

Mannuzza S, Klein R, Bessler A, Malloy P, LaPadula M . Adult outcome of hyperactive boys. Educational achievement, occupational rank, and psychiatric status. Arch Gen Psychiatry. 1993; 50(7):565-76. DOI: 10.1001/archpsyc.1993.01820190067007. View

Keenan K, Wakschlag L, Danis B, Hill C, Humphries M, Duax J . Further evidence of the reliability and validity of DSM-IV ODD and CD in preschool children. J Am Acad Child Adolesc Psychiatry. 2007; 46(4):457-468. DOI: 10.1097/CHI.0b013e31803062d3. View

Lambert N . Adolescent outcomes for hyperactive children. Perspectives on general and specific patterns of childhood risk for adolescent educational, social, and mental health problems. Am Psychol. 1988; 43(10):786-99. DOI: 10.1037//0003-066x.43.10.786. View

Lahey B, Loeber R, Quay H, Applegate B, Shaffer D, Waldman I . Validity of DSM-IV subtypes of conduct disorder based on age of onset. J Am Acad Child Adolesc Psychiatry. 1998; 37(4):435-42. DOI: 10.1097/00004583-199804000-00022. View

Biederman J, Faraone S, Milberger S, Jetton J, Chen L, Mick E . Is childhood oppositional defiant disorder a precursor to adolescent conduct disorder? Findings from a four-year follow-up study of children with ADHD. J Am Acad Child Adolesc Psychiatry. 1996; 35(9):1193-204. DOI: 10.1097/00004583-199609000-00017. View

Mannuzza S, Klein R, Abikoff H, Moulton 3rd J . Significance of childhood conduct problems to later development of conduct disorder among children with ADHD: a prospective follow-up study. J Abnorm Child Psychol. 2004; 32(5):565-73. DOI: 10.1023/b:jacp.0000037784.80885.1a. View

Hechtman L, Weiss G, Perlman T . Hyperactives as young adults: past and current substance abuse and antisocial behavior. Am J Orthopsychiatry. 1984; 54(3):415-425. DOI: 10.1111/j.1939-0025.1984.tb01507.x. View

10.

Burt S, McGue M, Krueger R, Iacono W . Sources of covariation among the child-externalizing disorders: informant effects and the shared environment. Psychol Med. 2005; 35(8):1133-44. PMC: 2242350. DOI: 10.1017/s0033291705004770. View

11.

Carey G . Cholesky problems. Behav Genet. 2005; 35(5):653-65. DOI: 10.1007/s10519-005-5355-9. View

12.

Willoughby M, Curran P, Costello E, Angold A . Implications of early versus late onset of attention-deficit/hyperactivity disorder symptoms. J Am Acad Child Adolesc Psychiatry. 2000; 39(12):1512-9. DOI: 10.1097/00004583-200012000-00013. View

13.

Satterfield J, Schell A . A prospective study of hyperactive boys with conduct problems and normal boys: adolescent and adult criminality. J Am Acad Child Adolesc Psychiatry. 1997; 36(12):1726-35. DOI: 10.1097/00004583-199712000-00021. View

14.

Moffitt T . Adolescence-limited and life-course-persistent antisocial behavior: a developmental taxonomy. Psychol Rev. 1993; 100(4):674-701. View

15.

DOnofrio B, Van Hulle C, Waldman I, Rodgers J, Harden K, Rathouz P . Smoking during pregnancy and offspring externalizing problems: an exploration of genetic and environmental confounds. Dev Psychopathol. 2008; 20(1):139-64. PMC: 3737574. DOI: 10.1017/S0954579408000072. View

16.

Lahey B, Applegate B, Waldman I, Loft J, Hankin B, Rick J . The structure of child and adolescent psychopathology: generating new hypotheses. J Abnorm Psychol. 2004; 113(3):358-85. DOI: 10.1037/0021-843X.113.3.358. View

17.

Lahey B, Van Hulle C, Waldman I, Rodgers J, DOnofrio B, Pedlow S . Testing descriptive hypotheses regarding sex differences in the development of conduct problems and delinquency. J Abnorm Child Psychol. 2006; 34(5):737-55. DOI: 10.1007/s10802-006-9064-5. View

18.

Dominicus A, Skrondal A, Gjessing H, Pedersen N, Palmgren J . Likelihood ratio tests in behavioral genetics: problems and solutions. Behav Genet. 2006; 36(2):331-40. DOI: 10.1007/s10519-005-9034-7. View

19.

Applegate B, Lahey B, Hart E, Biederman J, Hynd G, Barkley R . Validity of the age-of-onset criterion for ADHD: a report from the DSM-IV field trials. J Am Acad Child Adolesc Psychiatry. 1997; 36(9):1211-21. View

20.

Lahey B, Pelham W, Loney J, Kipp H, Ehrhardt A, Lee S . Three-year predictive validity of DSM-IV attention deficit hyperactivity disorder in children diagnosed at 4-6 years of age. Am J Psychiatry. 2004; 161(11):2014-20. DOI: 10.1176/appi.ajp.161.11.2014. View