Is Serum Matrix Metalloproteinase 9 a Useful Biomarker in Detection of Colorectal Cancer? Considering Pre-analytical Interference That May Influence Diagnostic Accuracy

Overview

Journal Br J Cancer

Specialty Oncology

Date 2008 Jul 24

PMID 18648367

Citations 5

Authors

K Jung

Affiliations

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References

Jung K, Laube C, Lein M, Lichtinghagen R, Tschesche H, Schnorr D . Kind of sample as preanalytical determinant of matrix metalloproteinase 2 and 9 and tissue inhibitor of metalloproteinase 2 in blood. Clin Chem. 1998; 44(5):1060-2. View

Lomholt A, Frederiksen C, Christensen I, Brunner N, Nielsen H . Plasma tissue inhibitor of metalloproteinases-1 as a biological marker? Pre-analytical considerations. Clin Chim Acta. 2007; 380(1-2):128-32. DOI: 10.1016/j.cca.2007.01.022. View

Souza-Tarla C, Uzuelli J, Machado A, Gerlach R, Tanus-Santos J . Methodological issues affecting the determination of plasma matrix metalloproteinase (MMP)-2 and MMP-9 activities. Clin Biochem. 2005; 38(5):410-4. DOI: 10.1016/j.clinbiochem.2005.02.010. View

Hurst N, Stocken D, Wilson S, Keh C, Wakelam M, Ismail T . Elevated serum matrix metalloproteinase 9 (MMP-9) concentration predicts the presence of colorectal neoplasia in symptomatic patients. Br J Cancer. 2007; 97(7):971-7. PMC: 2360395. DOI: 10.1038/sj.bjc.6603958. View

Mannello F, Luchetti F, Canonico B, Papa S . Effect of anticoagulants and cell separation media as preanalytical determinants on zymographic analysis of plasma matrix metalloproteinases. Clin Chem. 2003; 49(11):1956-7. DOI: 10.1373/clinchem.2003.022145. View

COOPER T, Eisen A, Stricklin G, Welgus H . Platelet-derived collagenase inhibitor: characterization and subcellular localization. Proc Natl Acad Sci U S A. 1985; 82(9):2779-83. PMC: 397649. DOI: 10.1073/pnas.82.9.2779. View

Murphy G, Reynolds J, Bretz U, Baggiolini M . Collagenase is a component of the specific granules of human neutrophil leucocytes. Biochem J. 1977; 162(1):195-7. PMC: 1164583. DOI: 10.1042/bj1620195. View

Wilson S, Wakelam M, Hobbs R, Ryan A, Dunn J, Redman V . Evaluation of the accuracy of serum MMP-9 as a test for colorectal cancer in a primary care population. BMC Cancer. 2006; 6:258. PMC: 1654179. DOI: 10.1186/1471-2407-6-258. View

Meisser A, Cohen M, Bischof P . Concentrations of circulating gelatinases (matrix metalloproteinase-2 and -9) are dependent on the conditions of blood collection. Clin Chem. 2004; 51(1):274-6. DOI: 10.1373/clinchem.2004.041707. View

10.

Gerlach R, Uzuelli J, Souza-Tarla C, Tanus-Santos J . Effect of anticoagulants on the determination of plasma matrix metalloproteinase (MMP)-2 and MMP-9 activities. Anal Biochem. 2005; 344(1):147-9. DOI: 10.1016/j.ab.2005.04.038. View

11.

Makowski G, Ramsby M . Use of citrate to minimize neutrophil matrix metalloproteinase-9 in human plasma. Anal Biochem. 2003; 322(2):283-6. DOI: 10.1016/j.ab.2003.07.030. View

12.

Mannello F, Tonti G . Gelatinase concentrations and zymographic profiles in human breast cancer: matrix metalloproteinases circulating in plasma are better markers for the subclassification and early prediction of cancer: the coagulation/fibrinolysis pathways alter the.... Int J Cancer. 2007; 121(1):216-8. DOI: 10.1002/ijc.22652. View

13.

Opdenakker G, Van den Steen P, Dubois B, Nelissen I, Van Coillie E, Masure S . Gelatinase B functions as regulator and effector in leukocyte biology. J Leukoc Biol. 2001; 69(6):851-9. View

14.

Mannello F, Tonti G, Papa S . Matrix metalloproteinase inhibitors as anticancer therapeutics. Curr Cancer Drug Targets. 2005; 5(4):285-98. DOI: 10.2174/1568009054064615. View

15.

Zucker S, Cao J . Measurement of matrix metalloproteinases in serum of patients with melanoma: snarled in technical pitfalls. Clin Cancer Res. 2005; 11(14):5069-70. DOI: 10.1158/1078-0432.CCR-05-0774. View

16.

Jung K, Lein M, Laube C, Lichtinghagen R . Blood specimen collection methods influence the concentration and the diagnostic validity of matrix metalloproteinase 9 in blood. Clin Chim Acta. 2001; 314(1-2):241-4. DOI: 10.1016/s0009-8981(01)00679-9. View

17.

Santos-Martinez M, Medina C, Jurasz P, Radomski M . Role of metalloproteinases in platelet function. Thromb Res. 2007; 121(4):535-42. DOI: 10.1016/j.thromres.2007.06.002. View

18.

Mannello F, Tonti G, Tanus-Santos J, Gerlach R . Silicate increases the release of MMP-9 forms in peripheral blood: why gelatin zymography differs significantly in citrate plasma and serum obtained with or without clot activators. Clin Chem. 2007; 53(11):1981-2. DOI: 10.1373/clinchem.2007.090548. View

19.

Ryan A, Wilson S, Wakelam M, Warmington S, Dunn J, Hobbs R . A prospective study to assess the value of MMP-9 in improving the appropriateness of urgent referrals for colorectal cancer. BMC Cancer. 2006; 6:251. PMC: 1635060. DOI: 10.1186/1471-2407-6-251. View

20.

Wu C, Wu M, Chiang E, Chen Y, Chen C, Chi N . Plasma matrix metalloproteinase-9 level is better than serum matrix metalloproteinase-9 level to predict gastric cancer evolution. Clin Cancer Res. 2007; 13(7):2054-60. DOI: 10.1158/1078-0432.CCR-06-2299. View