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Suppression of Male Courtship by a Drosophila Pheromone Receptor

Overview
Journal Nat Neurosci
Date 2008 Jul 22
PMID 18641642
Citations 98
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Abstract

In male Drosophila, chemosensory cues control many aspects of social behavior. We found that males with a mutated Gustatory receptor 32a gene (Gr32a) show high courtship toward males and mated females, indicating that GR32a functions as a pheromone receptor for a male inhibitory pheromone. Notably, we discovered that tarsal Gr32a-expressing neurons were essential for courtship suppression and projected to the ventrolateral protocerebrum, implying direct communication of chemosensory neurons with a higher-order brain structure.

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