Repair of Damage Caused by UV- and X-irradiation in the Amoeboflagellate Naegleria Gruberi

Overview

Journal Radiat Environ Biophys

Specialties Biophysics
Environmental Health
Oncology
Radiology

Date 1991 Jan 1

PMID 1857761

Authors

S Hillebrandt

I Muller

Affiliations

Soon will be listed here.

Abstract

Cysts of Naegleria gruberi have a normal UV- and an extremely high X-ray resistance compared to other protozoans. Caffeine and 3-aminobenzamide applied to excysting amoeba after irradiation in the encysted state (UV and X-rays) by feeding with drug-containing bacteria increased lethality, while fractionated irradiation (UV) and liquid-holding (UV and X-rays) increased survival. Illumination with visible light after UV-irradiation restored almost 100% viability. The results are discussed in regard to the activity of repair mechanisms.

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