Hsp70/nitric Oxide Relationship in Apoptotic Modulation During Obstructive Nephropathy

Overview

Journal Cell Stress Chaperones

Publisher Elsevier

Specialty Cell Biology

Date 2008 Jun 20

PMID 18563630

Citations 4

Authors

Walter Manucha

Patricia Valles

Affiliations

Soon will be listed here.

Abstract

The functional integrity of the kidney depends on normal development as well as on physiological cell turnover. Apoptosis induction is essential for these mechanisms. Multiple mechanisms are unleashed during obstructive nephropathy, one of the most complex being programmed cell death that leads to renal tubular atrophy and tubular loss. This review will focus on the interaction of nitric oxide and Hsp70 and on the regulation of renal antiapoptotic and protective oxidative stress responses.

Citing Articles

Heat shock protein 70/nitric oxide effect on stretched tubular epithelial cells linked to WT-1 cytoprotection during neonatal obstructive nephropathy.

Mazzei L, Cuello-Carrion F, Docherty N, Manucha W Int Urol Nephrol. 2017; 49(10):1875-1892.

PMID: 28711961 DOI: 10.1007/s11255-017-1658-z.

Urinary Proteomics Yield Pathological Insights for Ureteropelvic Junction Obstruction.

Froehlich J, Kostel S, Cho P, Briscoe A, Steen H, Vaezzadeh A Mol Cell Proteomics. 2016; 15(8):2607-15.

PMID: 27215552 PMC: 4974339. DOI: 10.1074/mcp.M116.059386.

Mediators and mechanisms of heat shock protein 70 based cytoprotection in obstructive nephropathy.

Mazzei L, Docherty N, Manucha W Cell Stress Chaperones. 2015; 20(6):893-906.

PMID: 26228633 PMC: 4595437. DOI: 10.1007/s12192-015-0622-z.

Oxidative stress and its significant roles in neurodegenerative diseases and cancer.

Thanan R, Oikawa S, Hiraku Y, Ohnishi S, Ma N, Pinlaor S Int J Mol Sci. 2014; 16(1):193-217.

PMID: 25547488 PMC: 4307243. DOI: 10.3390/ijms16010193.

References

Nagai-Kusuhara A, Nakamura M, Mukuno H, Kanamori A, Negi A, Seigel G . cAMP-responsive element binding protein mediates a cGMP/protein kinase G-dependent anti-apoptotic signal induced by nitric oxide in retinal neuro-glial progenitor cells. Exp Eye Res. 2006; 84(1):152-62. DOI: 10.1016/j.exer.2006.09.010. View

Gabai V, Meriin A, Mosser D, Caron A, Rits S, Shifrin V . Hsp70 prevents activation of stress kinases. A novel pathway of cellular thermotolerance. J Biol Chem. 1997; 272(29):18033-7. DOI: 10.1074/jbc.272.29.18033. View

Bautista A, SPITZER J . Inhibition of nitric oxide formation in vivo enhances superoxide release by the perfused liver. Am J Physiol. 1994; 266(5 Pt 1):G783-8. DOI: 10.1152/ajpgi.1994.266.5.G783. View

Harbrecht B, Stadler J, Demetris A, Simmons R, Billiar T . Nitric oxide and prostaglandins interact to prevent hepatic damage during murine endotoxemia. Am J Physiol. 1994; 266(6 Pt 1):G1004-10. DOI: 10.1152/ajpgi.1994.266.6.G1004. View

Balch W, Morimoto R, Dillin A, Kelly J . Adapting proteostasis for disease intervention. Science. 2008; 319(5865):916-9. DOI: 10.1126/science.1141448. View

Chevalier R . Obstructive nephropathy: towards biomarker discovery and gene therapy. Nat Clin Pract Nephrol. 2006; 2(3):157-68. DOI: 10.1038/ncpneph0098. View

Chan W, Krieg Jr R, Ward K, Santos Jr F, Lin K, Chan J . Progression after release of obstructive nephropathy. Pediatr Nephrol. 2001; 16(3):238-44. DOI: 10.1007/s004670000519. View

Hegarty N, Young L, Kirwan C, ONeill A, Bouchier-Hayes D, Sweeney P . Nitric oxide in unilateral ureteral obstruction: effect on regional renal blood flow. Kidney Int. 2001; 59(3):1059-65. DOI: 10.1046/j.1523-1755.2001.0590031059.x. View

Clancy R, Abramson S . Nitric oxide, an endothelial cell relaxation factor, inhibits neutrophil superoxide anion production via a direct action on the NADPH oxidase. J Clin Invest. 1992; 90(3):1116-21. PMC: 329973. DOI: 10.1172/JCI115929. View

10.

Miyajima A, Chen J, Poppas D, Vaughan Jr E, Felsen D . Role of nitric oxide in renal tubular apoptosis of unilateral ureteral obstruction. Kidney Int. 2001; 59(4):1290-303. DOI: 10.1046/j.1523-1755.2001.0590041290.x. View

11.

Ito K, Chen J, Seshan S, Khodadadian J, Gallagher R, El Chaar M . Dietary arginine supplementation attenuates renal damage after relief of unilateral ureteral obstruction in rats. Kidney Int. 2005; 68(2):515-28. DOI: 10.1111/j.1523-1755.2005.00429.x. View

12.

Ischiropoulos H, Zhu L, Chen J, Tsai M, Martin J, Smith C . Peroxynitrite-mediated tyrosine nitration catalyzed by superoxide dismutase. Arch Biochem Biophys. 1992; 298(2):431-7. DOI: 10.1016/0003-9861(92)90431-u. View

13.

Liu X, Kim C, Yang J, Jemmerson R, Wang X . Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c. Cell. 1996; 86(1):147-57. DOI: 10.1016/s0092-8674(00)80085-9. View

14.

Kasinath B, Mariappan M, Sataranatarajan K, Lee M, Feliers D . mRNA translation: unexplored territory in renal science. J Am Soc Nephrol. 2006; 17(12):3281-92. DOI: 10.1681/ASN.2006050488. View

15.

Mertens J, Gibson N, Lau S, Monks T . Reactive oxygen species and DNA damage in 2-bromo-(glutathion-S-yl) hydroquinone-mediated cytotoxicity. Arch Biochem Biophys. 1995; 320(1):51-8. DOI: 10.1006/abbi.1995.1341. View

16.

ALBINA J, Cui S, Mateo R, Reichner J . Nitric oxide-mediated apoptosis in murine peritoneal macrophages. J Immunol. 1993; 150(11):5080-5. View

17.

Kanner J, Harel S, GRANIT R . Nitric oxide as an antioxidant. Arch Biochem Biophys. 1991; 289(1):130-6. DOI: 10.1016/0003-9861(91)90452-o. View

18.

Chevalier R, Chung K, Smith C, Ficenec M, Gomez R . Renal apoptosis and clusterin following ureteral obstruction: the role of maturation. J Urol. 1996; 156(4):1474-9. View

19.

Kim Y, Kim T, Seol D, Talanian R, Billiar T . Nitric oxide suppression of apoptosis occurs in association with an inhibition of Bcl-2 cleavage and cytochrome c release. J Biol Chem. 1998; 273(47):31437-41. DOI: 10.1074/jbc.273.47.31437. View

20.

Manucha W, Carrizo L, Ruete C, Valles P . Apoptosis induction is associated with decreased NHE1 expression in neonatal unilateral ureteric obstruction. BJU Int. 2007; 100(1):191-8. DOI: 10.1111/j.1464-410X.2007.06840.x. View