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High Rate of Intestinal Colonization with Extended-spectrum-beta-lactamase-producing Organisms in Household Contacts of Infected Community Patients

Overview
Specialty Microbiology
Date 2008 Jun 20
PMID 18562591
Citations 55
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Abstract

Fecal carriage of extended-spectrum-beta-lactamase (ESBL)-producing organisms was detected in 70% of index cases of patients (n = 40) with community-acquired infections due to ESBL producers and reached 16.7% in household contacts (n = 54). A total of 66% of ESBL-producing organisms from index cases were indistinguishable from isolates from household contacts by pulsed-field gel electrophoresis. Patients with community infections and members of their households represent a reservoir for ESBL producers, increasing dispersal of resistance in healthy people.

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