Serum Alpha-fetoprotein Predicts Treatment Outcome in Chronic Hepatitis C Patients Regardless of HCV Genotype

Overview

Journal PLoS One

Specialties General Medicine
Science

Date 2008 Jun 12

PMID 18545682

Citations 6

Authors

Hendy Abdoul

Vincent Mallet

Stanislas Pol

Arnaud Fontanet

Affiliations

Soon will be listed here.

Abstract

We examined the association between serum alpha-fetoprotein (AFP) level and sustained virological response (SVR) in 93 chronic hepatitis C patients. The SVR rate was much higher among patients with serum AFP levels below rather than above the median value (5.7 ng/ml) (58.7% and 19.2%, respectively; P<0.0001). Serum AFP should be added to the list of factors predictive of treatment response in chronic hepatitis C.

Citing Articles

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Pretreatment Predictors of Response to PegIFN-RBV Therapy in Egyptian Patients with HCV Genotype 4.

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Serum Adiponectin, Vitamin D, and Alpha-Fetoprotein in Children with Chronic Hepatitis C: Can They Predict Treatment Response?.

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Serum alpha-fetoprotein level is higher in hepatitis C than hepatitis B infected chronic liver disease patients.

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