Coexistence of Amplitude and Frequency Modulations in Intracellular Calcium Dynamics

Overview

Journal Phys Rev E Stat Nonlin Soft Matter Phys

Publisher American Physical Society

Specialties Biophysics
Physiology
Public Health

Date 2008 Jun 4

PMID 18517322

Citations 23

Authors

Maurizio De Pitta

Vladislav Volman

Herbert Levine

Giovanni Pioggia

Danilo De Rossi

Eshel Ben-Jacob

Affiliations

Soon will be listed here.

Abstract

The complex dynamics of intracellular calcium regulates cellular responses to information encoded in extracellular signals. Here we study the encoding of these external signals in the context of the Li-Rinzel model. We show that by control of biophysical parameters the information can be encoded in amplitude modulation (AM), frequency modulation (FM), or mixed (AM and FM) modulation. We briefly discuss the possible implications of this role of information encoding for astrocytes.

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