Immunology of Dermatophytosis

Overview

Journal Mycopathologia

Specialties Microbiology
Pharmacology

Date 2008 May 15

PMID 18478362

Citations 27

Authors

Sandro Rogerio Almeida

Affiliations

Soon will be listed here.

Abstract

The immune response to infection by dermatophytes ranges from a non-specific host mechanism to a humoral and cell-mediated immune response. The currently accepted view is that a cell-mediated immune response is responsible for the control of dermatophytosis. Indeed, some individuals develop a chronic or recurrent infection mediated by the suppression of a cell-mediated immune response. The immune response to Trichophyton is unusual in that this fungus can elicit both immediate hypersensitivity (IH) and delayed-type hypersensitivity (DTH) in different individuals when they are submitted to a skin test reaction. Understanding the nature and function of the immune response to dermatophytes is an exciting challenge that might lead to novel approaches in the treatment and immunological prophylaxis of dermatophytosis.

Citing Articles

Host-Pathogen Interaction and Resistance Mechanisms in Dermatophytes.

Dubljanin E, Zunic J, Vujcic I, Colovic Calovski I, Sipetic Grujicic S, Mijatovic S Pathogens. 2024; 13(8).

PMID: 39204257 PMC: 11357293. DOI: 10.3390/pathogens13080657.

Fungal primary and opportunistic pathogens: an ecological perspective.

de Hoog S, Tang C, Zhou X, Jacomel B, Lustosa B, Song Y FEMS Microbiol Rev. 2024; 48(5).

PMID: 39118380 PMC: 11409879. DOI: 10.1093/femsre/fuae022.

A Clinical-Mycological Study of Dermatophytosis in Western India with Focus on Antifungal Drug Resistance as a Factor in Recalcitrance.

Shah S, Vyas H, Shah B, Jangid N, Choudhary A, Gehlawat T Indian J Dermatol. 2023; 68(2):234.

PMID: 37275803 PMC: 10238971. DOI: 10.4103/ijd.ijd_999_22.

Immunopathogenesis of Dermatophytoses and Factors Leading to Recalcitrant Infections.

Sardana K, Gupta A, Mathachan S Indian Dermatol Online J. 2021; 12(3):389-399.

PMID: 34211904 PMC: 8202482. DOI: 10.4103/idoj.IDOJ_503_20.

Mixed Cutaneous Infection Caused by Leishmania and Dermatophytes: A Rare Coincidence or Immunological Fact.

Singh A, Kumar A, Pandey J, Gaur V, Tripathi P, Adhikari I Case Rep Dermatol Med. 2021; 2021:5526435.

PMID: 33763264 PMC: 7963913. DOI: 10.1155/2021/5526435.

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